USDOE Human Subjects Research Database Summary, Fiscal Year 1998
Listing of project identifier, principal investigator, funding, number of human subjects, and project title.
DOE Facilities:
Principal # Human
Project Identifier Investigator Funding Subjects
Argonne National Laboratory
ANL-95-93003 Huberman $0 0
Analysis of Differentiation Markers in Normal and Leukemic
Blood Cells
ANL-97-96/001 Brown-VanHooze $0 0
Validating a Model of the Effect of Operator Information
Processing Behavior on Performance
Totals: 2 Project(s) $0 0
Brookhaven National Laboratory
BNL-74-113 Som $0 0
Labeling of Blood Elements with Radioactive Nuclides
BNL-77-146 Sutherland $1,000 2
DNA Repair - Human and E. Coli Photoreactivating Enzymes
BNL-86-203 Fowler $0 0
Localization of Functional Brain Monoamine Oxidase with
11-C-Clorgyline, 11-C-Deprenyl and PET
BNL-88-216 Fowler $0 0
A Study of Carbon-11 Cocaine Binding in Human Brain and
Heart
BNL-88-217 Fowler $0 0
The Use of Oxygen-15-Labeled Water to Assess Cerebral Blood
Flow
BNL-89-220 Fowler $0 0
Whole Body Distribution of 11-C-Labeled Cogentin in Humans
BNL-89-222 Dilmanian $252,677 21
New and Old Models in Body Composition: Ethnic Specificity
BNL-89-225 Dilmanian $85,650 27
Nutritional and Intestinal Consequences of Immunodeficiency
States
BNL-90-229 Srivastava $0 0
Sn-117m (4+) DTPA in the Treatment of Osseous Metastases
BNL-91-C15 Breitenstein $175,000 3,200
Health Surveillance System
BNL-91-C24 Sutherland $30,000 10
Photoreactivation in Human Skin
BNL-92-243 Fowler $352,000 16
Dopamine D2 Receptor Availability Measured with
Carbon-11-Labeled Raclopride
BNL-93-249 Fowler $0 0
Imaging the Dopamine Presynaptic Neuron with 11-C
Methylphenidate
BNL-94-144B Fowler $598,000 23
Evaluation of 18-FDG in the Diagnosis of Glucose Metabolism
in the Human Body (Cocaine Abusers)
BNL-94-144C Fowler $10,000 2
Evaluation of 18-FDG in the Diagnosis of Glucose Metabolism
in the Human Body (Tumors)
BNL-94-144D Fowler $40,000 2
Evaluation of 18-FDG in the Diagnosis of Glucose Metabolism
in the Human Body (Alcoholics)
BNL-94-144E Fowler $160,000 32
Evaluation of 18-FDG in the Diagnosis of Glucose Metabolism
in the Human Body (Alzheimer's)
BNL-94-144F Fowler $0 0
Evaluation of 18-FDG in the Diagnosis of Glucose Metabolism
in the Human Body (Schizophrenics)
BNL-94-254 Wang $0 0
Evaluation of Tumors with PET and SPECT
BNL-94-255 Fowler $0 0
11-C-L-Deprenyl-D2 for MAO B Mapping
BNL-94-257 Kaplan $300,000 39
Improvement of Fission Track Analysis (FTA) of Urine Samples
from the Nuclear Test Personnel Program at USDSWA
BNL-94-258 Fowler $0 0
Studies of Brain Aging
BNL-94-C25 Dilmanian $8,000 0
Studies of Human Anatomical Specimens with the Multiple
Energy Computed Tomography (MECT) System at the NSLS
BNL-95-249B Fowler $0 0
Imaging the Dopamine Presynaptic Neuron with 11-C
Methylphenidate (4 injections)
BNL-95-255B Fowler $0 0
11-C-L-Deprenyl-D2 and 18-FDG for Study of Neurodegenerative
Diseases
BNL-95-255C Fowler $8,000 1
[11C]Clorgyline for MAO A Mapping and [11C]L-Deprenyl-D2 for
MAO B Mapping
BNL-95-260 Coderre $0 0
Boron Neutron Capture Therapy of Glioblastoma Multiforme at
the Brookhaven Medical Research Reactor (BMRR)
BNL-95-260A Coderre $500,000 1
Boron Neutron Capture Therapy (BNCT) of Glioblastoma
Multiforme at the BMRR (Prior Radiation)
BNL-96-203B Fowler $0 0
The Use of Parnate to Assess if 11C-Clorgyline Binds to MAO
A in Human Brain and Liver
BNL-96-216B Fowler $96,000 3
Occupation of Dopamine Transporters by Pharmacological Doses
of Cocaine
BNL-96-216C Fowler $0 0
Dopamine Transporter Occupancy by Oral Methlyphenidate
BNL-96-243A Fowler $0 0
Dopamine D2 Receptor Availability Measured with
Carbon-11-Raclopride(Naloxone Administration)
BNL-96-249C Fowler $0 0
Dopamine Transporter Occupancy by Oral Methylphenidate
BNL-96-257B Kaplan $150,000 6
Blood and Urine Analysis for Pu-239
BNL-96-258B Fowler $105,000 5
Studies of Alcohol Withdrawal
BNL-96-265 Springer $499,000 27
General Magnetic Resonance Imaging (MRI) and Spectroscopic
(MRS) Studies of Human Subjects
BNL-96-266 Coderre $700,000 10
BNCT of GBM at the BMRR: A Phase I/II Dose Escalation Study
BNL-96-268 Fowler $0 0
Brain Imaging Studies in Obesity
BNL-97-216D Fowler $0 0
Dopamine Transporter Occupancy by Intravenous
Methylphenidate
BNL-97-216E Fowler $0 0
PET Studies of the Dopamine System in Smokers
BNL-97-243E Fowler $48,000 2
Effects of Exercise on 11C-Raclopride Binding and
Test-Retest Reproducibility for Measured 11C-Raclopride
Binding Obtained with 2D and 3D Acquisition Modes
BNL-97-264 Susskind $15,000 4
99m Tc DTPA Lung Clearance in Radiation Injury
BNL-97-271 Yang $150,000 1
Quantitative Studies on the Oncogenic and Cytogenetic
Effects of Energetic Iron Particles in Mammalian Cells
BNL-97-272 Fowler $15,000 30
Genetics of Dopamine in Brain
BNL-97-274 Srivastava $30,000 2
Biodistribution of Tin-117m Stannic Citrate
BNL-97-276 Dilmanian $40,000 10
3-Methylhistidine Kinetics as an Indicator of Muscle Mass
and Metabolism
BNL-97-C27 Chanana $0 5
Clinical Trials of BNCT at MIT
BNL-97-C28 Dewey $0 0
Autoradiographic Studies of Nicotinic Receptors in Post
Mortem Human Brain
BNL-98-216F Fowler $0 0
Occupation of Dopamine Transporters by Cocaine
BNL-98-266A Coderre $100,000 0
Boron Neutron Capture Therapy of Glioblastoma Multiforme at
the Brookhaven Medical Research Reactor: A Phase I/II Dose
Escalation Study (FDA IND 43,317, Protocol #5)
BNL-98-277 Fowler $210,000 10
Brain Imaging Studies in Methamphetamine Abusers
BNL-98-278 Hetherington $120,000 18
Spectroscopic Evaluation of Human Epilepsy
BNL-98-279 (replaces 216E) Fowler $80,000 5
PET Studies of the Effects of Tobacco Smoke on the Human
Brain
BNL-98-280 Volkow $0 0
Spectroscopic Studies in Drug Abusers
BNL-98-281 Pan $30,000 4
Cerebral Metabolism in Ketosis and Epilepsy: A Spectroscopic
Study at 4T
BNL-98-282 Pan $40,000 3
Evaluation of Multiple Sclerosis by 1H MR Spectroscopy
BNL-98-283 Pan $30,000 1
Cerebral Metabolism in Functional Stimulation: A Combined
1H-13C Magnetic Resonance and PET Study
BNL-98-284 Fowler $0 0
PET Evaluation of the Effect of Ginko Biloba on Brain
Monoamine Oxidase (MAO)
BNL-98-285 Pan $60,000 6
Regional Ethanol Uptake Kinetics and MRI Visibility of Human
Brain by 1H MRI Imaging
BNL-98-286 Coderre $100,000 0
Two Fraction Boron Neutron Capture Therapy of Debulked
Glioblastoma Multiforme at the Brookhaven Medical Research
Reactor: A Phase I/II Dose Escalation Study (FDA IND 43,317,
Protocol #6)
BNL-98-287 Coderre $100,000 0
Two Fraction Boron Neutron Capture Therapy of Non-Debulked
Glioblastoma Multiforme at the Brookhaven Medical Research
Reactor: A Phase I/II Dose Escalation Study (FDA IND 43,317,
Protocol #7)
BNL-98-288 Coderre $100,000 0
Boron Neutron Capture Therapy of Recurrent Glioblastoma
Multiforme at the Brookhaven Medical Research Reactor: A
Phase I/II Dose Escalation Study (FDA IND 43,317, Protocol
#8)
BNL-98-289 Fowler $0 0
PET Studies of L-Deprenyl (Selegiline)
BNL-98-290 Capala $5,000 1
Lymphocyte Damage Following Irradiation at the BMRR
BNL-98-291(Replaces 216) Fowler $0 0
Determination of DAT Occupancy by Oral Doses of
Methylphenidate
BNL-98-292 (Replaces 216D) Fowler $0 0
Determination of DAT Occupancy by Intravenous
Methlyphenidate
BNL-98-293 (replaces 216B) Fowler $112,000 4
Determination of DAT Occupancy by Cocaine as a Function of
Different Routes of Administration (Intravenous, Snorted and
Smoked)
BNL-98-294 (Replaces 216F) Fowler $0 0
Determination of DAT Occupancy by Cocaine after an Oral Dose
of Methylphenidate
BNL-98-295 (Replaces 144B) Fowler $0 0
PET Studies of Cocaine Abuse: Response to Methylphenidate
BNL-98-296 Rooney $0 1
Brain Water Content and Blood-Brain Barrier Permeability in
Multiple Sclerosis
BNL-98-C29 Kaplan $0 0
Techa River Cohort Bioassay
Totals: 71 Project(s) $5,455,327 3,534
Fermilab Neutron Therapy Facility
FNAL-98-98-98-01 Shafer $10,000 38
Impedance-Controlled Microcurrent Therapy for Cancer
Treatment Sequelae
Totals: 1 Project(s) $10,000 38
Idaho National Engineering and Environmental Laboratory
INEEL-90-95-001 Hartenstein $0 23
Federal Aviation Administration (FAA) Explosive Detection
System and Independent Validation and Verification Project
INEEL-95-INEEL-IRB-97-003 Pepp $150,000 2,383
The Employee Effects Of Downsizing in the Nuclear Industry.
INEEL-95-004 Rice $0 2,200
Concealed Weapons Detection System
INEEL-97-INEL-97-001 Thompson $114,000 10
Development of Immunological Sensor Test Kits for Forensic
Samples
INEEL-98-INEEL-IRB-98-001 Markowitz $372,494 60
Medical Surveillance For Former INEEL Workers
INEEL-98-INEEL-IRB-98-002 English $0 30
Performance Test for Detection of Explosives
Totals: 6 Project(s) $636,494 4,706
Lawrence Berkeley National Laboratory
LBNL-75-001-H02 Budinger $68,200 31
Experimental Medicine Clinical
LBNL-75-102-H01 Castro $200,000 600
Treatment of Cancer with Heavy Charged Particles
LBNL-77-057-H02 Rubin $0 0
Studies of Lipoproteins and Lipid Protein Interactions
LBNL-79-106-H02 Krauss $57,400 302
Lipoproteins and Atherogenesis in Transgenic Animals
LBNL-79-108-H01 Stampfer $534,000 1
Characterization of Human Mammary Cells
LBNL-80-001-H01 Budinger $0 0
Myocardial Flow, Function, and Metabolism by PET & MRI
(Cardiovascular Flow and Metabolism)
LBNL-82-001-H04 Budinger $0 0
Quantitative Cardiovascular Research
LBNL-84-001-H03 Budinger $0 5
Alzheimer's Disease as a Systemic Disorder
(Formerly: Cardiovascular Relationships in Alzheimer's
Disease)
LBNL-88-073-H02 Jagust $60,000 22
Longitudinal SPECT & PET Studies of Dementia
LBNL-88-107-H07 Williams $0 0
Lipoprotein Subfractions and Coronary Heart Disease During
25-Year Follow-Up
LBNL-90-007-H01 Melhorn $120,000 50
Hemoglobin Conversion to Pro-Oxidants by Cigarette Smoke
LBNL-90-068-H01 Narla $38,480 0
Red Cell Deformability In Vitro and Survival In Vivo
LBNL-90-107-H02 Williams $180,000 0
Weight Set Point and HDL Levels in Long-Distance Runners
LBNL-90-110-H01 Nordahl $0 12
Metabolic Effects of Serotonin Antagonism in Schizophrenia
LBNL-91-068-H03 Narla $145,800 15
Red Cell Membrane
LBNL-91-073-H01 Jagust $0 0
Alcohol and Memory: A PET Study
LBNL-91-107-H01 Williams $280,000 2,000
National Runner's Health Study
LBNL-92-065-H01 Maguire $0 1
The Oxidant and Antioxidant Balance in Wounds (Leukocyte
Function in Periodontal Disease)
LBNL-92-068-H02 Narla $28,900 0
Rheological and Adherence Properties of Sickle Cells
LBNL-92-106-H04 Krauss $334,000 9
Genetic and Metabolic Factors Affecting Response of Lp(a) to
Dietary Fat (formerly Genetic Influences on Dietary Fat
Response )
LBNL-92-107-H05 Williams $0 70
Effects of Running on HDL and LDL Subclasses of MZ Twins
LBNL-94-093-H01 Tribble $212,000 36
Oxidative Implications of Lipoprotein Heterogeneity
LBNL-94-114-H02 Lockett $40,000 2
3-D Analysis of Genetic Instability in Breast Cancer
LBNL-95-073-H03 Jagust $100,000 22
Subcortical Infarction, Cortical Metabolism and Dementia
LBNL-95-109-H01 Fisk $20,000 0
Healthy Buildings Intervention Research
LBNL-96-068-H04 Narla $3,300 1
Cellular Consequences of Hemoglobin Membrane Structure
LBNL-96-106-H05 Krauss $25,500 1
Analysis of Lipoprotein Remnants in Subjects with Small,
Dense LDL
LBNL-96-109-H02 Gadgil $0 0
Demonstration and Field Test of Air Jacket Technology
LBNL-97-057-H03 Forte $74,500 0
Plasma Antioxidative Enzymes as Indicators of Smoke Injury
LBNL-97-110-H02 Nordahl $53,000 0
Napa State Hospital Agreement
LBNL-97-135-H01 Daisey $0 0
Effects of Indoor Surfaces on Exposures to ETS
LBNL-98-087-H01 Eberling $0 0
Brain Imaging with [F-18]-Fluorometatyrosine in Parkinson's
Disease
LBNL-98-107-H06 Williams $0 3,240
National Health Survey on the Internet
LBNL-98-110-H03 Nordahl $0 4
Sex Differences of Dopamine Metabolism
LBNL-98-139-H01 William $0 0
Breast Cancer Specific PET Instrumentation
Totals: 35 Project(s) $2,575,080 6,424
Lawrence Livermore National Laboratory
LLNL-88-105 Jones $2,040,000 231
Radiation Genotoxicity from Chernobyl Accident
LLNL-88-111 Tucker $10,000 6
Cytogenetic Studies
LLNL-89-106 Biermann $280,000 17
Protective Breathing Equipment (Respirators) Testing
LLNL-90-105 Carrano $1,000 1
LLNL Human Genome Center
LLNL-90-108 Wyrobek $5,000 10
Detection of Aneuploid Human Sperm by in situ Hybridization
and Image Analysis
LLNL-91-102 Langlois $90,000 50
Glycophorin A-based Somatic Cell Mutation Measurements in
Blood Samples from Normal Individuals
LLNL-91-109 Andresen $100,000 30
Ultratrace Hair Analysis
LLNL-92-105 Tittiranonda $172,000 50
The Effects of Ergonomically Designed Computer Keyboards on
the Incidence of Cumulative Trauma Disorders among VDT
Workers
LLNL-94-105 Wyrobek $116,000 2
Investigation of the Relationship between Numerical
Chromosomal Aneuploidy in Sperm and Offspring
LLNL-95-115 Felton $200,000 3
Determining Metabolism Differences by Urine Analysis
LLNL-95-119 Lucas $0 0
Background Translocation Frequencies in Humans (former
title is "Chromosome Painting")
LLNL-95-126 Turteltaub $171,000 5
Influence of Heterocyclic Amine Metabolic Polymorphisms on
Bioactivation of PhIP in the Human Colon
LLNL-96-103 Turteltaub $250,000 6
Does Tamoxifen cause DNA Damage in Human Tissues
LLNL-96-104 Turteltaub $50,000 0
Do Trace Levels of Aflatoxin B1 cause DNA Damage in Human
Tissues
LLNL-96-105 Freeman $20,000 16
A Comparison of the use of 41Ca Tracer and Conventional
Biomarkers to Assess Bone Turnover in Healthy Adults.
LLNL-96-106 Lucas $0 0
Chernobyl Dosimetry
LLNL-96-108 Pluth $0 0
Genetic and Molecular Analysis of a Normal Human Population
LLNL-96-109 Wyrobek $116,000 97
Age Effects on the Incidence of Genetic and Physiological
Defects in Human Sperm
LLNL-96-110 Kinney $60,000 26
Characterization of Dentin
LLNL-96-111 Ng $50,000 20
MIR Speech Science Experiments on the Human Vocal Tract.
LLNL-96-113 Vogel $20,000 0
The Dynamics of Folate Metabloism in Adults
LLNL-96-114 Colston $10,000 18
Optical Diagnosis of Periodontal Disease (Protocol 97-111
was formally LLNL-97-111 in FY97 Database)
LLNL-97-100 Balhorn $0 0
Biochemical Analysis of Individual Human Sperm for IVF
LLNL-97-101 Bommarito $2,000 25
Physiological Responses of the Eye during Video Display
Terminal (VDT) Work
LLNL-97-102 Bench $0 13
Assessment of Dermal Exposure to Metals and Metal Compounds
LLNL-97-103 Mohrenweiser $320,000 60
Genetic Variation in Genes of DNA Repair
LLNL-97-105 Tucker $5,000 1
Pesticides: Health, Fertility and Reproductive Risks
LLNL-97-106 Turteltaub $20,000 4
Dosimetry of Aflatoxin B2 in Humans
LLNL-97-108 Fitch $0 0
Electronic Steghoscope with Digital Signal Processing
LLNL-97-110 Olsen $0 0
Generation of Contiguous Sequence-ready DNA Clones in Human
and Mouse
LLNL-97-112 Turteltaub $20,000 3
Metabolism and Macromolecular Adduct Formation of the Food
Mutagen MelQx in Humans
LLNL-98-100 Turteltaub $20,000 3
Study to Establish if DNA Damage is caused through Ingesting
Secondary Amines together with Sodium Nitrate or Nitrite and
if it can be Prevented with Chemopreventive Agents
LLNL-98-102 Lucas $0 0
Evaluation of Chromosome Damage to Uranium Workers in
Namibia for Assessment of Health Risk.
LLNL-98-104 Vogel $74,271 1
Elucidating Dynamics of Beta-carotene Metabolism in Adults
LLNL-98-105 Everett $15,000 2
Optical Diagnosis through Blood
LLNL-98-106 Mendelsohn $10,000 0
Melanoma and other Mortality Rates in LLNL Employees
LLNL-98-107 Freeman $0 0
Measurement of Historically Administered 41Ca
LLNL-98-109 Noonan $20,000 16
Development of Improved Methods for the Detection of
Individual Sensitivity to Beryllium and Identification of
Immunologic and Genetic Factors (see LANL-96-05 FY98
database)
LLNL-98-111 Tucker $0 0
Chromosome Aberration Persistence Study
LLNL-98-112 Tucker $15,000 20
Perchloroethylene Exposure Study
LLNL-98-116 Trebes $4,000 20
Thermospectrometry for Body Temperature Measurement
LLNL-98-120 Freeman $0 0
Measurement of Previously Administered 41Ca
LLNL-98-121 Sathyam $0 0
Optical Diagnosis of Skin Abnormalities
LLNL-98-122 Colston $1,000 1
Design of a Knee Immobilizer
LLNL-98-123 Kallman $0 0
Optically Parallel Ultrasound System
LLNL-98-97-116 Layton $13,050 104
LLNL/AHS Study of Home-Cooked Foods
Totals: 46 Project(s) $4,300,321 861
Los Alamos National Laboratory
LANL-52-91 LANL 06 Voelz $0 19
Manhattan Project Plutonium Workers Health Study
LANL-76-90 LANL 07 Reinert $165,000 6
Acceptance Testing for Air-Line Supplied Air-Suits
LANL-91-03 Sklar $0 0
Ligand-Receptor G Protein Dynamics and Neutrophil Response
(formally LANL-91-91-LANL-03 in FY97 database)
LANL-96-05 Marrone $383,000 150
Development of Improved Methods for the Detection of
Individual Sensitivity to Beryllium (formerly
LANL-96-96-LANL-05 in FY97 database) (see LLNL-98-109 FY98
database)
LANL-97-02 Pepper $300,000 1,506
Prevention of Stress and the Health Consequences of
Workplace Downsizing and Reorganization (formerly
LANL-95-97-LANL-02 in FY97 database)
LANL-98-01 Wray $0 0
Development and Testing of A Fieldable Prototype Noninvasive
Intracranial Pressure Measurement System
LANL-98-02 Kraus, Jr. $0 0
Neuromagnetic Mapping of Functional Centers in the Human
Brain
LANL-98-03 Lehnert $0 4
Use of Human Peripheral Blood Samples in Structure Function
Based Poisoning of Anthrax Toxins
LANL-98-04 Lehnert $0 4
Use of Human Peripheral Blood Samples in Structural Biology
of Bacterial Toxins
Totals: 9 Project(s) $848,000 1,689
Los Alamos National Laboratory (Federal Workers Program)
LANL-98-98-LANL-E5 Schwartz $6,000 350
Medical Surveillance for Former Department of Energy Workers
Totals: 1 Project(s) $6,000 350
Oak Ridge Institute for Science and Education
ORAU-78-96 Goans $50,000 2
Use of Ca-DTPA and Zn-DTPA for Chelation Therapy of Heavy
Metals
ORAU-79-63 Goans $25,000 305
The U.S. Radiation Accident Registry Follow-Up Program
(formally ORAU-80-63 in FY97 database)
ORAU-80-58 Cragle $500 8
Whole Blood Procurement, Consent for Research Waiver Form
and Payment Authorization
ORAU-80-60 Cragle $66,000 22,625
Comprehensive Epidemiology Study of Department of Energy
Atomic Workers
ORAU-80-61 Goans $25,000 2
The DTPA Registry Follow-Up Program
ORAU-89-60a Cragle $623 18,574
Amendment - Comprehensive Epidemiology Study of Department
of Energy Atomic Workers
ORAU-91-81 Goans $0 0
Use of Prussian Blue for Internal Decontamination of
Radiocesium
ORAU-91-82a Cragle $2,000 8
Studies to Establish and Define ORAU Laboratory Standards
for Lymphocyte Proliferation Tests (LPT)
ORAU-92-87 Cragle $857,186 370
Oak Ridge Y-12 Beryllium Workers Follow-Up Study, Phase II:
Screening for Beryllium Sensitivity and Definitive Diagnosis
of Chronic Beryllium Disease
ORAU-97-BU-1 Pepper $300,000 776
Prevention of Stress and Health Consequences of Workplace
Downsizing and Reorganization: Oak Ridge Review
ORAU-97-UC1 Bingham $0 0
Medical Surveillance Program for Construction Workers at
Oak Ridge, TN : Phase I
ORAU-98-100 Hart $0 4
Frequency of Hand/Wrist Problems Among Sign Language
Communicators
Totals: 12 Project(s) $1,326,309 42,674
Oak Ridge National Laboratory
ORNL-93-17 Jenkins $300,000 278
Measurement of Environmental Tobacco Smoke Constituents in
Occupied Spaces
ORNL-94-33 Buchanan $40,000 30
Characterization of Components of Fingerprints
ORNL-94-38 Draper $50,000 4
Advanced Robotics for Remanufacturing and Aircraft Support
Functions
ORNL-95-45 Gailey $0 0
Physiological Responses to EMF (Electric and Magnetic
Fields) in Humans
ORNL-96-53 Gailey $563,272 1,000
Survey of Personal Magnetic Field Exposure
ORNL-96-54 Gailey $64,000 20
Development of Field Exposure Predictions Models
ORNL-96-55 Jenkins $15,000 0
Environmental Tobacco Smoke: Composition, Exposure, and
Measurement
ORNL-98-47 Gailey $14,100 16
Biomarkers of Magnetic Field Exposure (formerly Melatonin
Levels of Electric Utility Workers)
ORNL-98-52 Gailey $707,000 59
Physiological Responses to Electric and Magnetic Fields in
Humans (formally ORNL-97-ORNL-52 in FY97 database)
ORNL-98-56 Sega $0 0
Study of Neurotransmitters in Children with ADD or ADHD
Totals: 10 Project(s) $1,753,372 1,407
Pacific Northwest National Laboratory
PNNL-94-4 Thrall $50 6
PBPK Breath Analysis Instrumentation Demonstration
PNNL-96-17 Roye $80,000 45
Breast Cancer Prevention, Education, and Detection
PNNL-96-20 Cameron $179,000 3
Study of Heat Stress and Performance in Carpenters at DOE
Sites
PNNL-96-4 Richman $14,000 18
Field Evaluation of Polarized and Full Spectrum Polarized
Lighting
PNNL-97-1 Barnhart $206,000 352
Comprehensive Occupational Health Surveillance
PNNL-97-10 Takaro $38,000 445
Screening For Chronic Beryllium Disease at Hanford
PNNL-97-2 Barnhart $783,000 1,162
Medical Surveillance Program/Former DOE Workers
PNNL-97-5 Ringen $970,000 500
Former Workers' Notification and Medical Screening -
Hanford
PNNL-97-6 Roye $190,000 75
Inherited Breast Cancer, Identification, Education,
Counseling and Testing of High Risk Patients in a Military
Setting
PNNL-97-8 Thrall $0 0
Fundamental Research on Solvent-Laden Soils
PNNL-98-7 Brodkin $50,000 0
Surveillance Methods for Solvent-related Hepatotoxicity
PNNL-98-5 Mong $0 0
Advanced Techniques in Latent Fingerprint and
Visualization
PNNL-98-1 Bradbury $232,000 377
Military Relocation Questionnaire
Totals: 13 Project(s) $2,742,050 2,983
Rocky Flats Environmental Technology Site
RFET-68-RF-94-02 Gottschall $0 0
United States Transuranium Registry
RFET-80-RF-94-01 Gottschall $360,000 286
Former Radiation Worker Recall Program (RFET-80-RF-94-03
from FY97 database has been combined with this project)
RFET-91-RF-94-06 Stange $2,150,000 1,500
Rocky Flats Beryllium Health Surveillance Program
Totals: 3 Project(s) $2,510,000 1,786
Sandia National Laboratories
SNL-97-06 Schaub $180,000 4
Advanced Attack Methods (formerly Wall Breaching Tests)
SNL-97-08 Williams $450 37
The Effects of a Four-Week Walking Program on the Blood
Lipid Profiles
SNL-98-01 Sandoval $0 0
Border Warning/Intrusion Detection Radar
SNL-98-02 Swahlan $25,000 2
Access Delay Technology Base Support
SNL-98-03 Zelicoff $100,000 1,000
Hepatitis C Research Study
SNL-98-04 Murray $25,000 1
Performance Evaluation of the DKL Model 2.0 Lifeguard
SNL-98-07 Boswell $354 297
Development and Evaluation of a Stress-Based Health
Promotion Model in an Organizational Setting Using
Structural Equation Modeling
Totals: 7 Project(s) $330,804 1,341
DOE Facility Totals: 216 Projects $22,493,757 67,793
Non-DOE Facilities:
Principal # Human
Project Identifier Investigator Funding Subjects
Agency for Toxic Substances and Disease Registry
ATSDR-96-1594 Tatham $0 81,600
Hanford Infant Mortality and Fetal Death Analysis
ATSDR-96-1624 Burg $0 5,933
National Exposure Registry: Iodine-131 Subregistry Site
Specific Protocol, Hanford Nuclear Reservation, State of
Washington
Totals: 2 Project(s) $0 87,533
Beckman Laser Institute/UC Irvine
BLI-91-ER61227 Berns $114,236 38
A Center of Excellence for Laser Applications in Medicine
(formally UCI-91-ER61227 in FY97 database)
Totals: 1 Project(s) $114,236 38
Beth Israel Deaconess Medical Center
BIDMC-94-1 Zamenhof $0 0
Phase-I BNCT Trial of Peripheral Melanoma
BIDMC-96-2 Zamenhof $550,000 7
Phase-I BNCT Trial of Glioblastoma Multiforme and
Metastatic Melanoma to the Brain
Totals: 2 Project(s) $550,000 7
The Center to Protect Workers' Rights
CPWR-98-001 Ringen $455,559 30,000
The Augusta Building Trades Medical Screening Program for
Savannah River
Totals: 1 Project(s) $455,559 30,000
Columbia University
CU-93-62433 Bergmann $262,742 14
Detection and Assessment Using Position Emission Tomography
of Defects in Myocardial Fatty Acid Utilization
Totals: 1 Project(s) $262,742 14
Columbia University - Eye Research
CU-95-95EH89658 Worgul $325,058 5,400
Ocular Radiation Effects in Chernobyl Liquidators
Totals: 1 Project(s) $325,058 5,400
Consortium for Risk Evaluation w/ Stakeholder Participation
CRESP-95-E96-108 Burger $200,000 800
Use of Ecological Resources at DOE Sites
CRESP-96-058M Yurkow $10,000 11
The Examination of Peripheral Blood Lymphocyte Proteins as
Predictors of Risk
CRESP-96-27-0009-E Takaro $46,727 0
Laboratory Evaluation of Field Collected Cells
CRESP-96-E97-026 Greenberg $21,000 210
CRESP-SLUDGE Surveys and Interviews
CRESP-97-041-96 Frumkin $16,456 0
Cohort Study of Former Employees of a Chloralkalai Plant in
Brunswick, Georgia
CRESP-97-26-0807-B/C Faustman $10,475 11
Human Reproductive Endocrine Effects of Controlled Toluene
Exposure
CRESP-97-27-0228-C Takaro $108,355 70
Screening for Chronic Beryllium Disease at Hanford
CRESP-97-27-0295-X Faustman $14,281 0
Analysis of Gene Expression Changes in Isolated
Uroepithelial Cells
Totals: 8 Project(s) $427,294 1,102
Lovelace Respiratory Research Institute
LRRI-95-IRB#95-030/IRB#96027 Guilmette $251,000 121
In Vivo Measurements of Lead-210 in Former Uranium Miners
(formally ITRI-95-IRB#95-030/IRB#96027 in FY97 database)
Totals: 1 Project(s) $251,000 121
Medical University of South Carolina
MUSC-98-DG-FC03-97SF21513 Hoel $555,351 1,000
Savannah River Site Former Production Workers Health
Surveillance Program
Totals: 1 Project(s) $555,351 1,000
National Academy of Sciences (NAS)
NAS-90-DEFG0590ER60960 Douple $11,800,000 2,985
Activities of National Academy of Sciences in Relation to
the Radiation Effects Research Foundation (RERF)
Totals: 1 Project(s) $11,800,000 2,985
Nevada Test Site
NTS-96-001 Pepper $630,000 137
Medical Surveillance for Former Department of Energy
Workers at the Nevada Test Site
Totals: 1 Project(s) $630,000 137
Princeton University
PU-96-DE-FG02-96ER62202 Fresco $0 0
Development of Affinity Technology for Isolating Individual
Human Chromosomes by Third Strand Binding
Totals: 1 Project(s) $0 0
Sloan-Kettering Institute for Cancer Research
SKI-86-ER60407 Larson $0 0
Improving Cancer Treatment with Cyclotron Produced
Radionuclides
SKI-95-ER62039 Larson $0 0
Pharmacokinetics of Genetically Engineered Antibody Forms
Using Positron Emission Tomography
Totals: 2 Project(s) $0 0
St. Mary's Hospital Saccomanno Research Institute
SMHSRI-95-DE-FG03-95ER62060/A0 Carstea $251,424 100
Identification of Human Lung Cancer Susceptibility Genes
SMHSRI-97-DE-FG02-90E60939 Saccomanno $93,000 250
Early Lung Cancer Detection in Uranium Miners with Abnormal
Sputum Cytology
Totals: 2 Project(s) $344,424 350
The Ohio State University
OSU-95-95H0240 Goodman $300,000 23
Pharmacokinetics and Biodistribution of Sodium Borocaptate
in Patients with Anaplastic Astrocytomas / Glioblastoma
Multiforme
Totals: 1 Project(s) $300,000 23
UCLA School of Medicine, Department of Pathology
UCLA-87-ER-60548 Gatti $5,800 10
Human Gene for Radiation Hypersensitivity
Totals: 1 Project(s) $5,800 10
University of California, Los Angeles
UCLA-92-639 Small $0 0
Mapping Dopamine Receptors with F-18 Fluorethylspiperone
UCLA-92-640 Small $0 0
Dopamine Transport and Storage Measured with DOPA
UCLA-93-654 Schelbert $2,000 17
Assessment of Myocardial Viability by N-13 Ammonia, F-18
Deoxyglucose and Positron Emission Tomography
UCLA-95-036 Small $0 0
Dopamine Transport and Storage Measured with [18F]
Fluoro-L-m-Tyrosine
UCLA-95-117 Schelbert $10,000 11
Measurement of Myocardial Blood Flow with N-13 Ammonia
UCLA-95-450 Czernin $9,000 18
Significance of Cardiac Allograft Vasculopathy
UCLA-96-082 Gambhir $0 1
Sparing/Recovery of Function after Hemispherectomy:
Analysis with Functional Imaging
UCLA-96-426 Czernin $5,000 4
Response of Coronary Vasomotion to Intravenous L-Arginine
UCLA-97-490 Hoh $0 0
Whole Body PET scanning with Flouride-18 and FDG
UCLA-98-021 Eisenberg $0 0
Human Subject Research Under Structural Biology & Molecular
Medicine Research Program
UCLA-98-039 Small $0 6
Beta-Amyloid Probes of Alzheimer's Disease
Totals: 11 Project(s) $26,000 57
University of Chicago
UCHI-86-DEFG0286ER60408 Rowley $1,237,741 125
Correlation of Chromosome Patterns in Leukemic Cells of
Patients with Exposure to Chemicals and/or Radiation
Totals: 1 Project(s) $1,237,741 125
University of Michigan Hospitals
UMH-87-DE-FG02-87ER60561 Kuhl $5,600 2
Advancing PET Science for New Measures of Brain Function
Totals: 1 Project(s) $5,600 2
University of Tennessee Medical Center-Knoxville
UTMC-92-IRB-0104 Smith $53,761 68
A Consortium to Develop the Medical Uses of NMR Imaging, NMR
Spectroscopy, and Positron Emission Tomography
UTMC-93-IRB-0555 Kabalka $88,200 4
An Evaluation of Fluorine-18 Labeled BPA-F in Patients with
Glioblastoma Multiforme Using Positron Emission Tomography
(PET)
Totals: 2 Project(s) $141,961 72
University of Vermont
UVT-83-DE-FG02-87ER60502 Albertini $0 0
Development of In Vitro Mutagenicity Testing Systems Using
T-Lymphocytes
UVT-97-DE-FG07-96ER62331 Albertini $216,304 21
A Novel Biomarker for Beryllium Sensitization in Humans
Totals: 2 Project(s) $216,304 21
University of Washington
UWA-92-26-009-E Trask $132,000 5
Analytical Cytogenetics and Gene Mapping
Totals: 1 Project(s) $132,000 5
Washington State University
WASU-68-50181 Kathren $1,372,000 892
United States Transuranium and Uranium Registries
Totals: 1 Project(s) $1,372,000 892
Columbia University - Chernobyl workers study
CU-98-ES09484 Worgul $187,543 42
A Long-Term Stable Bioindicator for Radiation Exposure
Totals: 1 Project(s) $187,543 42
Fred Hutchinson Cancer Research Center
FHCRC-89-CDC-200-89-0716 Davis $2,000,000 1,747
Hanford Thyroid Disease Study
Totals: 1 Project(s) $2,000,000 1,747
University of Colorado Health Sciences Center
UCHSC-92-U50/CCU808715 Ruttenber $250,000 89
Epidemiologic Evaluation of Childhood Leukemia and Paternal
Exposure to Ionizing Radiation
Totals: 1 Project(s) $250,000 89
Other Facility Totals: 49 Projects $21,590,613 131,772
Grand Totals: 265 Projects $44,084,370 199,565