USDOE Human Subjects Research Database Summary, Fiscal Year 1997
Listing of project identifier, principal investigator, funding, number of human subjects, and project title.
DOE Facilities:
Principal # Human
Project Identifier Investigator Funding Subjects
Argonne National Laboratory
ANL-95-93003 Huberman $35,000 6
Analysis of Differentiation Markers in Normal and Leukemic
Blood Cells
ANL-97-96/001 Brown-VanHooze $0 0
Validating a Model of the Effect of Operator Information
Processing Behavior on Performance
Totals: 2 Project(s) $35,000 6
Brookhaven National Laboratory
BNL-74-113 Som $0 0
Labeling of Blood Elements with Radioactive Nuclides
BNL-75-134 Bender $0 0
Mechanisms of Chromosomal Aberration Production
BNL-77-146 Sutherland $1,000 2
DNA Repair - Human and E. Coli Photoreactivating Enzymes
BNL-86-203 Fowler $0 0
Localization of Functional Brain Monoamine Oxidase with
11-C-Clorgyline, 11-C-Deprenyl and PET
BNL-86-210 Thomlinson $0 0
K-Edge Angiography with Synchrotron X-Rays
BNL-86-C1 Jones $0 0
Renal Sequelae of Excessive Lead Store
BNL-88-216 Fowler $0 0
A Study of Carbon-11 Cocaine Binding in Human Brain and
Heart
BNL-88-217 Fowler $0 0
The Use of Oxygen-15-Labeled Water to Assess Cerebral Blood
Flow
BNL-89-220 Fowler $0 0
Whole Body Distribution of 11-C-Labeled Cogentin in Humans
BNL-89-222 Dilmanian $22,500 9
New and Old Models in Body Composition: Ethnic Specificity
BNL-89-223 Dilmanian $0 0
Black and White Races, Body Composition and Osteoporosis
BNL-89-224 Dilmanian $0 0
The Effects of Strength Training and Weight Reduction on
Bone and Muscle Mass in Postmenopausal Women
BNL-89-225 Dilmanian $24,000 12
Nutritional and Intestinal Consequences of Immunodeficiency
States
BNL-90-229 Srivastava $285,000 0
Sn-117m (4+) DTPA in the Treatment of Osseous Metastases
BNL-91-C15 Breitenstein $175,000 3,200
Health Surveillance System
BNL-91-C24 Sutherland $30,000 10
Photoreactivation in Human Skin
BNL-92-243 Fowler $128,000 8
Dopamine D2 Receptor Availability Measured with
Carbon-11-Labeled Raclopride
BNL-92-246 Ma $0 0
Body Composition of Diabetic Patients with Hyperkalemia
BNL-92-C19 Srivastava $0 0
Clinical Evaluation of Two New Chelates for Labeling an
Anti-CEA Antibody with In-111 for Immunoscintigraphy
BNL-93-249 Fowler $16,000 2
Imaging the Dopamine Presynaptic Neuron with 11-C
Methylphenidate
BNL-93-252 Ma $0 0
Validation of a Method for Estimating Muscle Protein Mass
and Muscle Protein Breakdown in Humans
BNL-94-144B Fowler $240,000 24
Evaluation of 18-FDG in the Diagnosis of Glucose Metabolism
in the Human Body (Cocaine Abusers)
BNL-94-144C Fowler $10,000 2
Evaluation of 18-FDG in the Diagnosis of Glucose Metabolism
in the Human Body (Tumors)
BNL-94-144D Fowler $80,000 4
Evaluation of 18-FDG in the Diagnosis of Glucose Metabolism
in the Human Body (Alcoholics)
BNL-94-144E Fowler $150,000 30
Evaluation of 18-FDG in the Diagnosis of Glucose Metabolism
in the Human Body (Alzheimer's)
BNL-94-144F Fowler $10,000 2
Evaluation of 18-FDG in the Diagnosis of Glucose Metabolism
in the Human Body (Schizophrenics)
BNL-94-254 Wang $50,000 1
Evaluation of Tumors with PET and SPECT
BNL-94-255 Fowler $0 0
11-C-L-Deprenyl-D2 for MAO B Mapping
BNL-94-257 Kaplan $300,000 70
Improvement of Fission Track Analysis (FTA) of Urine Samples
from the Nuclear Test Personnel Program at USDSWA
BNL-94-258 Volkow $212,000 2
Studies of Brain Aging
BNL-94-C25 Dilmanian $8,000 0
Studies of Human Anatomical Specimens with the Multiple
Energy Computed Tomography (MECT) System at the NSLS
BNL-95-243B Fowler $96,000 3
Dopamine D2 Receptor Availability Measured with Carbon-11
Labeled Raclopride (Methylphenidate Administration)
BNL-95-249B Fowler $0 0
Imaging the Dopamine Presynaptic Neuron with 11-C
Methylphenidate (4 injections)
BNL-95-255B Fowler $0 0
11-C-L-Deprenyl-D2 and 18-FDG for Study of Neurodegenerative
Diseases
BNL-95-255C Fowler $0 0
[11C]Clorgyline for MAO A Mapping and [11C]L-Deprenyl-D2 for
MAO B Mapping
BNL-95-260 Chanana $300,000 11
Boron Neutron Capture Therapy of Glioblastoma Multiforme at
the Brookhaven Medical Research Reactor (BMRR)
BNL-95-260A Chanana $200,000 2
Boron Neutron Capture Therapy (BNCT) of Glioblastoma
Multiforme at the BMRR (Prior Radiation)
BNL-95-261 Wang $0 0
Effects of Boron Neutron Capture Therapy on Glucose
Metabolism of Glioblastoma Multiforme and Normal Brain
BNL-95-C22 Bender $0 0
DNA Repair Capacity and Familial Breast Cancer
BNL-96-203B Fowler $0 0
The Use of Parnate to Assess if 11C-Clorgyline Binds to MAO
A in Human Brain and Liver
BNL-96-216B Fowler $148,000 4
Occupation of Dopamine Transporters by Pharmacological Doses
of Cocaine
BNL-96-216C Fowler $224,000 7
Dopamine Transporter Occupancy by Oral Methlyphenidate
BNL-96-243A Fowler $0 0
Dopamine D2 Receptor Availability Measured with Carbon-11
Labeled Raclopride (Naloxone Administration)
BNL-96-243C Fowler $112,000 5
PET Scanning Study of Nefazadone and Paroxetine in Normal
Human Volunteers
BNL-96-249C Fowler $0 0
Dopamine Transporter Occupancy by Oral Methylphenidate
BNL-96-257B Kaplan $150,000 5
Blood and Urine Analysis for Pu-239
BNL-96-258B Fowler $120,000 4
Studies of Alcohol Withdrawal
BNL-96-265 Springer $409,000 44
General Magnetic Resonance Imaging (MRI) and Spectroscopic
(MRS) Studies of Human Subjects
BNL-96-266 Chanana $700,000 11
BNCT of GBM at the BMRR: A Phase I/II Dose Escalation Study
BNL-96-267 Thomlinson $20,000 2
Medical Imaging with Xenon K-Edge Dichromography
BNL-96-268 Fowler $126,000 6
Brain Imaging Studies in Obesity
BNL-96-270 Dilmanian $0 0
Weight Loss: Bone and Skeletal Muscle Homeostasis
BNL-96-C26 O'Hara $150,000 12
The Effects Of Alarm Processing and Display on Operator and
Plant Performance
BNL-97-216D Fowler $256,000 8
Dopamine Transporter Occupancy by Intravenous
Methylphenidate
BNL-97-216E Fowler $0 0
PET Studies of the Dopamine System in Smokers
BNL-97-243E Fowler $48,000 2
Effects of Exercise on 11C-Raclopride Binding and
Test-Retest Reproducibility for Measured 11C-Raclopride
Binding Obtained with 2D and 3D Acquisition Modes
BNL-97-264 Susskind $20,000 4
99m Tc DTPA Lung Clearance in Radiation Injury
BNL-97-271 Yang $150,000 1
Quantitative Studies on the Oncogenic and Cytogenetic
Effects of Energetic Iron Particles in Mammalian Cells
BNL-97-272 Fowler $15,000 31
Genetics of Dopamine in Brain
BNL-97-274 Srivastava $30,000 0
Biodistribution of Tin-117m Stannic Citrate
BNL-97-276 Dilmanian $40,000 0
3-Methylhistidine Kinetics as an Indicator of Muscle Mass
and Metabolism
BNL-97-C27 Chanana $315,000 5
Clinical Trials of BNCT at MIT
BNL-97-C28 Dewey $1,000 1
Autoradiographic Studies of Nicotinic Receptors in Post
Mortem Human Brain
Totals: 63 Project(s) $5,371,500 3,546
Consortium for Risk Evaluation w/ Stakeholder Participation
CRESP-96-27-0009-E Takaro $138,478 13
Laboratory Evaluation of Field Collected Cells
CRESP-96-X-0720 Williams $85,000 1,671
A Descriptive Analysis of Variables Related to Public
Education, Outreach, and Risk Communication at the Savannah
River Site
CRESP-97-041-96 Frumkin $14,378 175
Cohort Study of Former Employees of a Chloralkalai Plant in
Brunswick, Georgia
CRESP-97-26-0807-B/C Faustman $2,698 20
Human Reproductive Endocrine Effects of Controlled Toluene
Exposure
CRESP-97-27-0228-C Takaro $118,139 15
Screening for Chronic Beryllium Disease at Hanford
CRESP-97-27-0295-X Faustman $9,030 9
Analysis of Gene Expression Changes in Isolated
Uroepithelial Cells
Totals: 6 Project(s) $367,723 1,903
Idaho National Engineering and Environmental Laboratory
INEEL-90-95-001 Hartenstein $1 20
Federal Aviation Administration (FAA) Explosive Detection
System and Independent Validation and Verification Project
INEEL-95-004 Rice $235,000 6
Concealed Weapons Detection System
INEEL-96-INEL-96-001 Collins $18,300 0
An Industrial Hygiene Survey of a Waste Reduction Facility -
Heat
INEEL-97-INEEL-97-002 Leanna $500 200
Evaluation of Patient Satisfaction with Occupational Health
Nursing Service
INEEL-97-INEL-97-001 Thompson $114,000 11
Development of Immunological Sensor Test Kits for Forensic
Samples
Totals: 5 Project(s) $367,801 237
Lawrence Berkeley National Laboratory
LBNL-75-001-H02 Budinger $148,000 159
Experimental Medicine Clinical
LBNL-75-102-H01 Castro $200,000 600
Treatment of Cancer with Heavy Charged Particles
LBNL-77-057-H02 Forte $0 2
Cell and Molecular Biology of Lipoprotein Metabolism (Will
change in FY 98 to: Studies of Lipoproteins and Lipid
Protein Interactions)
LBNL-79-106-H02 Krauss $34,500 754
Lipoproteins and Atherogenesis in Transgenic Animals
LBNL-79-108-H01 Stampfer $608,000 1
Characterization of Human Mammary Cells
LBNL-80-001-H01 Budinger $0 0
Myocardial Flow, Function, and Metabolism by PET & MRI
(Cardiovascular Flow and Metabolism)
LBNL-82-001-H04 Budinger $0 0
Quantitative Cardiovascular Research
LBNL-84-001-H03 Budinger $30,000 0
Cardiovascular Relationships in Alzheimer's Disease
(Formerly: Cerebral Chemical Patterns in Alzheimer's
Disease)
LBNL-84-115-H01 Rubinstein $45,000 47
Lighting Technology
LBNL-88-073-H02 Jagust $120,000 5
Longitudinal SPECT & PET Studies of Dementia
LBNL-88-107-H07 Williams $0 0
Lipoprotein Subfractions and Coronary Heart Disease During
25-Year Follow-Up
LBNL-90-007-H01 Melhorn $188,000 50
Hemoglobin Conversion to Pro-Oxidants by Cigarette Smoke
LBNL-90-068-H01 Narla $254,676 10
Red Cell Deformability In Vitro and Survival In Vivo
LBNL-90-107-H02 Williams $180,000 83
Weight Set Point and HDL Levels in Long-Distance Runners
LBNL-90-110-H01 Nordahl $0 14
Metabolic Effects of Serotonin Antagonism in Schizophrenia
(Formerly: Hippocampal Metabolism in Schizophrenia)
LBNL-91-068-H03 Narla $1,432,101 20
Red Cell Membrane
LBNL-91-073-H01 Jagust $0 1
Alcohol and Memory: A PET Study
LBNL-91-091-H01 Chatterjee $80,704 0
Training and Basic Research Related to Health Effects of
Exposure to HZE Particles
LBNL-91-107-H01 Williams $0 2,000
National Runner's Health Study
LBNL-92-065-H01 Maguire $206,000 5
The Oxidant and Antioxidant Balance in Wounds (Leukocyte
Function in Periodontal Disease)
LBNL-92-068-H02 Narla $280,000 10
Rheological and Adherence Properties of Sickle Cells
LBNL-92-106-H04 Krauss $282,700 661
Genetic Influences on Dietary Fat Response
LBNL-92-107-H05 Williams $0 70
Effects of Running on HDL and LDL Subclasses of MZ Twins
LBNL-93-107-H04 Williams $27,000 0
Effects of Diet on HDL Subclasses
LBNL-94-093-H01 Tribble $153,240 19
Oxidative Implications of Lipoprotein Heterogeneity
LBNL-94-114-H02 Lockett $85,000 1
3-D Analysis of Genetic Instability in Breast Cancer
LBNL-95-073-H03 Jagust $100,000 34
Subcortical Infarction, Cortical Metabolism and Dementia
LBNL-95-109-H01 Fisk $28,426 0
Healthy Buildings Intervention Research
LBNL-96-068-H04 Narla $68,447 6
Cellular Consequences of Hemoglobin Membrane Structure
LBNL-96-106-H05 Krauss $49,700 20
Analysis of Lipoprotein Remnants in Subjects with Small,
Dense LDL
LBNL-96-109-H02 Gadgil $0 0
Demonstration and Field Test of Air Jacket Technology
LBNL-97-057-H03 Forte $0 0
Plasma Antioxidative Enzymes as Indicators of Smoke Injury
LBNL-97-110-H02 Nordahl $50,000 0
Napa State Hospital Agreement
LBNL-97-133-H02 Grondona $0 5
Urine Analysis of Pu-239
LBNL-97-135-H01 Daisey $0 0
Effects of Indoor Surfaces on Exposures to ETS
Totals: 35 Project(s) $4,651,494 4,577
Lawrence Livermore National Laboratory
LLNL-84-P-101-03 Gordon $20,000 5
Human Sperm Chromatin and Chromosomes
LLNL-88-105 Jones $1,000,000 200
Radiation Genotoxicity from Chernobyl Accident
LLNL-88-111 Tucker $5,000 15
Cytogenetic Studies
LLNL-89-106 Biermann $50,000 12
Protective Breathing Equipment (Respirators) Testing
LLNL-90-105 Carrano $22,000 3
Center for Genome Research
LLNL-90-108 Wyrobek $71,000 40
Detection of Aneuploid Human Sperm by In Situ Hybridization
and Image Analysis
LLNL-91-102 Langlois $60,000 50
Glycophorin A-based Somatic Cell Mutation Measurements in
Blood Samples from Normal Individuals
LLNL-91-109 Andresen $100,000 30
Ultratrace Hair Analysis
LLNL-92-105 Burastero $259,000 50
The Effects of Ergonomically Designed Computer Keyboards on
the Incidence of Cumulative Trauma Disorders Among VDT
Workers
LLNL-94-103 Vogel $0 10
Percutaneous Absorption of Radiolabeled Chemicals in Humans
LLNL-94-105 Wyrobek $116,000 40
Investigation of the Relationship between Numerical
Chromosomal Aneuploidy in Sperm and Offspring: A
Feasibility Study
LLNL-94-116 Azevedo $10,000 0
Personnel Detection and Imaging with Micropower Impulse
Radar
LLNL-94-117 Bogen $0 0
Direct Measurement of Uptake of Toxic Chemicals from Water,
Soil & Dust into Human Skin In Vivo, Phase I: Aqueous Expos
LLNL-95-109 Freeman $100,000 0
An Investigation of Human Calcium Kinetics Using 41Ca and
Stable Isotope Labeled Calcium
LLNL-95-110 Weber $10,000 0
Molecular Genetics of DNA Repair
LLNL-95-111 Wyrobek $10,000 0
Detection of Chromosomal Abnormalities in Sperm from Men
Carrying Specific Constitutive Chromosomal Genetic Factors
LLNL-95-115 Felton $200,000 12
Determining Metabolism Differences by Urine Analysis
LLNL-95-119 Lucas $100,100 5
Chromosome Painting
LLNL-95-126 Turteltaub $171,000 10
Influence of Heterocyclic Amine Metabolic Polymorphisms on
Bioactivation of PhIP in the Human Colon
LLNL-96-102 Tucker $25,000 300
Cytogenetic Blood Analyses of NCI-sponsored Studies
LLNL-96-103 Turteltaub $250,000 16
Does Tamoxifen Cause DNA Damage in Human Tissues
LLNL-96-104 Turteltaub $50,000 24
Do Trace Levels of Aflatoxin B1 Cause DNA Damage in Human
Tissures
LLNL-96-105 Freeman $20,000 16
A Comparison of the Use of 41Ca Tracer and Conventional
Biomarkers to Assess Bone Turnover in Healthy Adults.
LLNL-96-106 Anspaugh $0 0
Chernobyl Dosimetry
LLNL-96-107 Sesko $28,000 12
A Synergy of Science and Art
LLNL-96-108 Pluth $121,000 225
Genetic and Molecular Analysis of a Normal Human Population
LLNL-96-109 Wyrobek $144,000 105
Age Effects on the Incidence of Genetic and Physiological
Defects in Human Sperm
LLNL-96-110 Kinney $80,000 30
Characterization of Dentin
LLNL-96-111 Ng $20,000 5
MIR Speech Science Experiments on the Human Vocal Tract.
LLNL-96-114 Everett $20,000 3
Optical Diagnosis of Periodontal Disease.
LLNL-97-100 Balhorn $20,000 0
Biochemical Analysis of Individual Human Sperm for IVF.
LLNL-97-101 Bommarito $20,000 28
Physiological Responses of the Eye during Video Display
Terminal Work.
LLNL-97-102 Bench $20,000 25
Assessment of Dermal Exposure to Metals and Metal Compounds.
LLNL-97-103 Mohrenweiser $20,000 60
Genetic Variation in Genes of DNA Repair.
LLNL-97-105 Tucker $20,000 50
Pesticides: Health, Fertility and Reproductive Risks.
LLNL-97-106 Turteltaub $20,000 15
Dosimetry of Aflatoxin B2 in Humans.
LLNL-97-108 Fitch $20,000 50
Electronic Stefhoscope with Digital Signal Processing.
LLNL-97-110 Olsen $20,000 0
Generation of Contiguous Sequence-Ready DNA Clones in Human
and Mouse.
LLNL-97-111 Everett $20,000 25
Clinical Optical Diagnosis of Periodontal Disease.
LLNL-97-112 Turteltaub $20,000 7
Metabolism and Macromolecular Adduct Formation of the Food
Mutagen MelQx in Humans
Totals: 40 Project(s) $3,262,100 1,478
Los Alamos National Laboratory
LANL-52-91 LANL 06 Voelz $90,000 19
Manhattan Project Plutonium Workers Health Study
LANL-76-90 LANL 07 Reinert $100,000 7
Respirator Studies, Acceptance Testing Procedures for
Air-Line Supplied Air-Suits
LANL-91-90 LANL 04 Aine $285,208 1
Neuromagnetic Mapping of Multiple Visual Areas in Humans
LANL-91-91 LANL 03 Sklar $10,000 0
Ligand-Receptor G Protein Dynamics and Neutrophil Response
LANL-92-92 LANL 03 Reinert $100,000 3
Acceptance Testing of Hazardous Material Level "A" and
Level "B" Suits
LANL-94-94 LANL 02 Reinert $0 0
Testing of Hazmat Level "A" Suits with the NASA Liquid-Air
Breathing System
LANL-95-97 LANL 02 Pepper $300,000 300
The Employee Effects of Downsizing in the Nuclear Industry
LANL-96-96 LANL 02 Inkret $62,000 10
Applications of Mass Spectrometry to the Detection of
Plutonium Intakes
LANL-96-96 LANL 03 Reinert $20,000 4
Heat Stess and Durability Testing, Frahm-Tex Cool Suit
LANL-96-96 LANL 04 Reinert $125,000 5
Evaluation of Sensors and Methods for Auditory Canal
Temperature Measurements
LANL-96-96 LANL 05 Marrone $250,000 60
Improved Methods for Detection of Beryllium Sensitivity
LANL-96-96 LANL 06 Mourant $50,000 2
Optical Physiological Monitoring of the Brain
LANL-97-97 LANL 01 Reinert $28,000 0
Human Subject Aerosol Penetration Testing of 3M Abrasive
Blasting Hoods
LANL-97-97 LANL 03 Reinet $20,000 5
Heat Stress and Aerosol Testing of the Bechtel-Hanford Suits
Totals: 14 Project(s) $1,440,208 416
Oak Ridge Institute for Science and Education
ORAU-78-96 Goans $50,000 2
Use of Ca-DTPA and Zn-DTPA for Chelation Therapy of Heavy
Metals
ORAU-80-58 Littlefield $500 5
Whole Blood Procurement, Consent for Research Waiver Form
and Payment Authorization
ORAU-80-60 Cragle $0 3,695
Comprehensive Epidemiology Study of Department of Energy
Atomic Workers
ORAU-80-61 Goans $25,000 2
The DTPA Registry Follow-Up Program
ORAU-80-63 Goans $25,000 437
The U.S. Radiation Accident Registry Follow-Up Program
ORAU-89-60a Cragle $0 43,999
Amendment - Comprehensive Epidemiology Study of Department
of Energy Atomic Workers
ORAU-91-80 Dupree Ellis $0 0
Study of Morbidity and Mortality From Selected Causes Among
Oak Ridge Y-12 Sheet Metal Workers
ORAU-91-81 Goans $0 1
Use of Prussian Blue for Internal Decontamination of
Radiocesium
ORAU-91-82a Littlefield $2,000 35
Studies to Establish and Define ORAU Laboratory Standards
for Lymphocyte Proliferation Tests (LPT)
ORAU-92-87 Cragle $950,000 350
Oak Ridge Y-12 Beryllium Workers Follow-Up Study, Phase II:
Screening for Beryllium Sensitivity and Definitive Diagnosis
of Chronic Beryllium Disease
ORAU-94-91 McFee $20,000 4
Establishing Background Level of Chromosomal Translocations
ORAU-95-83 Dupree Ellis $7,714 423
Identification and Abstraction of Death Certificates for the
Agency for Toxic Substances and Disease Registry
ORAU-96-98 Tankersley $48,000 234
Improved Systems for Worker Exposure Surveillance
ORAU-97-OCAW1 Wages $50,000 194
Medical Surveillance for Former Gaseous Diffusion Plants,
Phase I: Needs Assessment
ORAU-97-UC1 Bingham $578,909 0
Medical Surveillance Program for Construction Workers at
Oak Ridge, TN
ORAU-97-99 Carroll $10,000 28
Effective Programs for Worker Notification: A Case Study on
Contamination of Worker Hands and Automobiles at a
Commercial Beryllium Machining Plant
Totals: 16 Project(s) $1,767,123 49,409
Oak Ridge National Laboratory
ORNL-93-17 Jenkins $230,000 1,729
Measurement of Environmental Tobacco Smoke Constituents in
Occupied Spaces
ORNL-94-33 Buchanan $75,000 24
Characterization of Components of Fingerprints (new title).
(old title)Development of Methods to Obtain Fingerprints
from Children for Forensic Applications.
ORNL-94-38 Draper $50,000 4
Advanced Robotics for Remanufacturing and Aircraft Support
Functions
ORNL-95-45 Gailey $150,000 40
Physiological Responses to Electric and Magnetic Fields
(EMF) in Humans
ORNL-95-50 Gailey $50,000 20
Development of Recommendations for Personal Exposure
Measurement of Electric and Magnetic Fields
ORNL-96-53 Gailey $200,000 200
Survey of Personal Magnetic Field Exposure
ORNL-96-54 Gailey $50,000 61
Development of Field Exposure Predictions Models
ORNL-96-55 Jenkins $10,000 0
Environmental Tobacco Smoke: Composition, Exposure, and
Measurement
ORNL-97-ORNL-52 Gailey $400,000 86
Physiological Responses to Electric and Magnetic Fields in
Humans
Totals: 9 Project(s) $1,215,000 2,164
Pacific Northwest National Laboratory
PNNL-94-4 Thrall $0 0
PBPK Breath Analysis Instrumentation Demonstration (See
PNNL-96-94-4 in FY96 database)
PNNL-95-3 Toth $40,000 20
Noninvasive Approach to Testing for H. Pylori Infections
Using Breath Analysis (See PNNL-96-95-3 in FY96 database)
PNNL-96-1 Collins $0 0
Imaging Neurological Processes of the Human Brain
PNNL-96-17 Roye $324,800 53
Breast Cancer Prevention, Education, and Detection
PNNL-96-20 Cameron $179,000 18
Study of Heat Stress and Performance in Carpenters at DOE
Sites (Courtesy Review)
PNNL-96-4 Richman $0 20
Field Evaluation of Polarized and Full Spectrum Polarized
Lighting
PNNL-97-1 Barnhart $300,000 569
Comprehensive Occupational Health Surveillance
PNNL-97-10 Barnhart $48,000 25
Screening For Chronic Beryllium Disease at Hanford
PNNL-97-2 Barnhart $450,000 618
Medical Surveillance Program/Former DOE Workers
PNNL-97-5 Ringen $0 0
Former Workers' Notification and Medical Screening -
Hanford
PNNL-97-6 Adams $702,000 120
Inherited Breast Cancer, Identification, Education,
Counseling and Testing of High Risk Patients in a Military
Setting
PNNL-97-8 Thrall $0 0
Fundamental Research on Solvent-Laden Soils
Totals: 12 Project(s) $2,043,800 1,443
Rocky Flats Environmental Technology Site
RFET-68-RF-94-02 Gottschall $0 0
United States Transuranium Registry
RFET-80-RF-94-01 Gottschall $550,000 259
Former Radiation Worker Recall Program
RFET-80-RF-94-03 Gottschall $0 25
1965 Fire Group
RFET-91-RF-94-86 Stange $2,352,692 1,500
Rocky Flats Beryllium Health Surveillance Program
Totals: 4 Project(s) $2,902,692 1,784
Sandia National Laboratories
SNL-94-01 Love $0 0
Personal Status Monitor
SNL-94-12 Osbourn $2,000 1
Calibration and Benchmarking Data for Machine Vision and
Image Classification
SNL-95-06 Bouchard $20,000 6
Acoustic Data Acquisition From Human Subjects
SNL-95-10 Bouchard $40,000 56
Video and Acoustic Data Acquisition From Human Subjects for
Personnel Identity Verification
SNL-95-11 Aurand $0 0
Radar Detection of Concealed Weapons
SNL-95-12 Ladd $15,000 2
Human Presence Detection Utilizing a Chemical Agent Monitor
SNL-96-03 Ladd $20,000 2
Remote Vital Sign Detection Utilizing Micropower Impulse
Radar Technology
SNL-96-04 Spencer $0 0
Commuter Aircraft Visual Inspection Reliability
SNL-96-05 Tucker $2,000 5
Visual Observer Tests
SNL-97-01 Little $15,000 6
3D Ultrasound Imaging for Diagnostic Imaging. II.
SNL-97-05 Linker $20,000 2,400
Sandia's Explosives Detection Portal
SNL-97-06 Swahlan $300,000 5
Wall Breaching Tests
SNL-97-08 Williams $330 76
The Effects of a Four-Week Walking Program on the Blood
Lipid Profiles
Totals: 13 Project(s) $434,330 2,559
The Ohio State University
OSU-95-95H0240 Goodman $300,000 2
Pharmacokinetics and Biodistribution of Sodium Borocaptate
in Patients with Anaplastic Astrocytomas / Glioblastoma
Multiforme
Totals: 1 Project(s) $300,000 2
University of California, Berkeley
UCB-92-ER61393 Duster $0 1
Pathways to Genetic Screening
Totals: 1 Project(s) $0 1
DOE Facility Totals: 221 Projects $24,158,771 69,525
Non-DOE Facilities:
Principal # Human
Project Identifier Investigator Funding Subjects
Beckman Laser Institute/UC Irvine
UCI-91-ER61227 Berns $143,654 28
A Center of Excellence for Laser Applications in Medicine
Totals: 1 Project(s) $143,654 28
Beth Israel Deaconess Medical Center
BIDMC-94-1 Zamenhof $550,000 0
Phase-I BNCT Trial of Peripheral Melanoma
BIDMC-96-2 Zamenhof $550,000 6
Phase-I BNCT Trial of Glioblastoma Multiforme and
Metastatic Melanoma to the Brain
Totals: 2 Project(s) $1,100,000 6
Columbia University - Eye Research
CU-95-95EH89658 Worgul $208,436 0
Ocular Radiation Effects in Chernobyl Liquidators
Totals: 1 Project(s) $208,436 0
Department of Molecular Biology, Princeton University
PU-96-DE-FG02-96ER62202 Fresco $208,084 2
Development of Affinity Technology for Isolating Individual
Human Chromosomes by Third Strand Binding
Totals: 1 Project(s) $208,084 2
Lovelace Respiratory Research Institute
ITRI-95-IRB#95-030/IRB#96027 Guilmette $267,700 105
In Vivo Measurements of Lead-210 in Former Uranium Miners
(See: Project ITRI-96-IRB#96-019 in FY96 Database)
Totals: 1 Project(s) $267,700 105
National Academy of Sciences (NAS)
NAS-90-DEFG0590ER60960 Douple $14,000,000 3,433
Activities of National Academy of Sciences in Relation to
the Radiation Effects Research Foundation (RERF)
Totals: 1 Project(s) $14,000,000 3,433
Sloan-Kettering Institute for Cancer Research
SKI-86-ER60407 Larson $20,001 1
Improving Cancer Treatment with Cyclotron Produced
Radionuclides
SKI-95-ER62039 Larson $0 0
Pharmacokinetics of Genetically Engineered Antibody Forms
Using Positron Emission Tomography
Totals: 2 Project(s) $20,001 1
St. Mary's Hospital Saccomanno Research Institute
SMHSRI-95-DE-FG03-95ER62060/A0 Carstea $147,232 100
Identification of Human Lung Cancer Susceptibility Genes
(See SMHCRI-95-DE-FG03-95ER62060/A0 in FY96 database)
SMHSRI-97-DE-FG02-90E60939 Saccomanno $66,924 270
Early Lung Cancer Detection in Uranium Miners with Abnormal
Sputum Cytology (See SMHCRI-97-DE-FG02-90E60939 in FY96
database)
Totals: 2 Project(s) $214,156 370
The University of Iowa
UI-97-ER61233 Soares $0 5
Development and Application of Subtractive Hybridization
Strategies to Facilitate Gene Discovery (See: Project
CU-91-2923R in FY96 Database)
Totals: 1 Project(s) $0 5
University of California, Los Angeles
UCLA-92-639 Small $0 0
Mapping Dopamine Receptors with F-18 Fluorethylspiperone
UCLA-92-640 Small $0 0
Dopamine Transport and Storage Measured with DOPA
UCLA-93-654 Schelbert $0 0
Assessment of Myocardial Viability by N-13 Ammonia, F-18
Deoxyglucose and Positron Emission Tomography (See
UCLA-47-87ER60615 in FY96 database)
UCLA-95-036 Small $0 0
Dopamine Transport and Storage Measured with [18F]
Fluoro-L-m-Tyrosine
UCLA-95-117 Schelbert $29,000 33
Measurement of Myocardial Blood Flow with N-13 Ammonia
UCLA-95-450 Czernin $15,000 42
Significance of Cardiac Allograft Vasculopathy (See
UCLA-96-450 in FY96 database)
UCLA-96-082 Gambhir $0 7
Sparing/Recovery of Function after Hemispherectomy:
Analysis with Functional Imaging
UCLA-96-426 Czernin $0 0
Response of Coronary Vasomotion to Intravenous L-Arginine
UCLA-97-490 Hoh $5,000 13
Whole Body PET scanning with Flouride-18 and FDG
Totals: 9 Project(s) $49,000 95
University of California, Los Angeles - School of Medicine
UCLA-87-ER60548 Gatti $236,000 24
Human Gene for Radiation Hypersensitivity
Totals: 1 Project(s) $236,000 24
University of Chicago
UCHI-86-DEFG0286ER60408 Rowley $1,237,741 125
Correlation of Chromosome Patterns in Leukemic Cells of
Patients with Exposure to Chemicals and/or Radiation
Totals: 1 Project(s) $1,237,741 125
University of Michigan Hospitals
UMH-79-NS15655 Kuhl $112,700 46
Positron Emission Tomography (PET) Study of the Biochemistry
and Metabolism of the Central Nervous System (CNS)
UMH-86-NS24896 Kuhl $107,500 43
Emission Computed Tomography of Local Cerebral Function
UMH-87-DE-FG02-87ER60561 Kuhl $0 0
Advancing PET Science for New Measures of Brain Function
Totals: 3 Project(s) $220,200 89
University of Tennessee Medical Center-Knoxville
UTMC-92-IRB-0104 Smith $0 0
A Consortium to Develop the Medical Uses of NMR Imaging, NMR
Spectroscopy, and Positron Emission Tomography
UTMC-93-IRB-0555 Kabalka $45,000 1
An Evaluation of Fluorine-18 Labeled BPA-F in Patients with
Glioblastoma Multiforme Using Positron Emission Tomography
(PET)
Totals: 2 Project(s) $45,000 1
University of Vermont
UVT-83-DE-FG02-87ER60502 Albertini $356,000 15
Development of In Vitro Mutagenicity Testing Systems Using
T-Lymphocytes
UVT-97-DE-FG07-96ER62331 Albertini $0 21
A Novel Biomarker for Beryllium Sensitization in Humans
Totals: 2 Project(s) $356,000 36
University of Washington
UWA-92-26-009-E Trask $132,000 5
Analytical Cytogenetics and Gene Mapping
Totals: 1 Project(s) $132,000 5
Washington State University
WASU-68-50181 Kathren $1,184,000 890
United States Transuranium and Uranium Registries
Totals: 1 Project(s) $1,184,000 890
Washington University
WUSM-93-61659 Bergmann $0 0
Detection and Assessment Using Position Emission Tomography
of Genetically Determined Defects in Myocardial Fatty Acid
Utilization
Totals: 1 Project(s) $0 0
Non-DOE Facility Totals: 33 Projects $19,621,972 5,215
Grand Totals: 254 Projects $43,780,743 74,740