USDOE Human Subjects Research Database Summary, Fiscal Year 1996

Listing of project identifier, principal investigator, funding, number of human subjects, and project title.

DOE Facilities:

 
                                     Principal                        # Human
Project Identifier                   Investigator           Funding   Subjects
 
Argonne National Laboratory
 
ANL-90-92005                         Giometti                    $0         0
           Two-dimensional Electrophoresis of Proteins from Human Blood
           Samples
 
ANL-95-93002                         Huberman               $35,000         2
           Analysis of Radiation Sensitive Markers in Normal Human
           White Blood Cells
 
ANL-95-93003                         Huberman               $35,000         3
           Analysis of Differentiation Markers in Normal and Leukemic
           Blood Cells
 
ANL-95-93004                         Giometti               $10,000         0
           Analysis of Cells Found in Human Milk
 
ANL-97-96/001                         Brown-VanHooze             $0         0
           Validating a Model of the Effect of Operator Information
           Processing Behavior on Performance
 
Totals:  5 Project(s)                                       $80,000         5
 
Brookhaven National Laboratory
 
BNL-74-113                           Som                         $0         0
           Labeling of Blood Elements with Radioactive Nuclides
 
BNL-75-134                           Bender                  $2,000         3
           Mechanisms of Chromosomal Aberration Production
 
BNL-77-146                           Sutherland              $1,000         2
           DNA Repair - Human and E. Coli Photoreactivating Enzymes
 
BNL-86-203                            Fowler               $177,000        25
           Localization of Functional Brain Monoamine Oxidase with
           11-C-Clorgyline, 11-C-Deprenyl and PET
 
BNL-86-210                           Thomlinson             $20,000         3
           K-Edge Angiography with Synchrotron X-Rays
 
BNL-86-C1                            Jones                       $0        59
           Renal Sequelae of Excessive Lead Store
 
BNL-88-216                           Fowler                  $7,000         1
           A Study of Carbon-11 Cocaine Binding in Human Brain and
           Heart
 
BNL-88-217                           Fowler                      $0         0
           The Use of Oxygen-15-Labeled Water to Assess Cerebral Blood
           Flow
 
BNL-89-220                           Dewey                       $0         0
           Whole Body Distribution of 11-C-Labeled Cogentin in Humans
 
BNL-89-222                           Ma                          $0         0
           New and Old Models in Body Composition: Ethnic Specificity
 
BNL-89-223                           Ma                          $0         0
           Black and White Races, Body Composition and Osteoporosis
 
BNL-89-224                           Ma                          $0         0
           The Effects of Strength Training and Weight Reduction on
           Bone and Muscle Mass in Postmenopausal Women
 
BNL-89-225                           Ma                          $0         0
           Nutritional and Intestinal Consequences of Immunodeficiency
           States
 
BNL-89-C13                           Coderre               $180,000         6
           Biodistribution of p-Boronophenylalanine in Patients with
           Malignant Melanoma and Malignant Brain Tumors
 
BNL-90-229                           Srivastava            $285,000        13
           Sn-117m (4+) DTPA in the Treatment of Osseous Metastases
 
BNL-91-C14                           Barancik                    $0         0
           UAW-Ford/BNL-IPAG Information System Research Demonstration
           Project: Phase I
 
BNL-91-C15                           Breitenstein          $162,000     3,200
           Health Surveillance System
 
BNL-91-C24                           Sutherland                  $0         0
           Photoreactivation in Human Skin
 
BNL-92-243                           Dewey                  $24,000        24
           Dopamine D2 Receptor Availability Measured with
           Carbon-11-Labeled Raclopride
 
BNL-92-245                           Leske                   $2,000       401
           Adult Fluoride Study
 
BNL-92-246                           Ma                          $0         0
           Body Composition of Diabetic Patients with Hyperkalemia
 
BNL-92-C19                           Srivastava                  $0         0
           Clinical Evaluation of Two New Chelates for Labeling an
           Anti-CEA Antibody with In-111 for Immunoscintigraphy
 
BNL-93-249                           Fowler                 $42,000         3
           Imaging the Dopamine Presynaptic Neuron with 11-C
           Methylphenidate
 
BNL-93-250                           Ma                      $8,000        20
           A Comparison of Different Techniques of Body Composition
           Analysis to Neutron Activation Analysis in Patients on
           Dialysis
 
BNL-93-252                           Ma                          $0         0
           Validation of a Method for Estimating Muscle Protein Mass
           and Muscle Protein Breakdown in Humans
 
BNL-94-144B                          Fowler                 $62,000         7
           Evaluation of 18-FDG in the Diagnosis of Glucose Metabolism
           in the Human Body (Cocaine Abusers)
 
BNL-94-144C                          Fowler                $115,000        13
           Evaluation of 18-FDG in the Diagnosis of Glucose Metabolism
           in the Human Body (Tumors)
 
BNL-94-144D                          Fowler                $266,000        15
           Evaluation of 18-FDG in the Diagnosis of Glucose Metabolism
           in the Human Body (Alcoholics)
 
BNL-94-144E                          Fowler                 $44,000        20
           Evaluation of 18-FDG in the Diagnosis of Glucose Metabolism
           in the Human Body (Alzheimer's)
 
BNL-94-144F                          Fowler                 $23,000         6
           Evaluation of 18-FDG in the Diagnosis of Glucose  Metabolism
           in the Human Body (Schizophrenics)
 
BNL-94-254                           Wang                   $50,000         0
           Evaluation of Tumors with PET and SPECT
 
BNL-94-255                           Fowler                 $57,000         4
           11-C-L-Deprenyl-D2 for MAO B Mapping
 
BNL-94-257                           Kaplan                  $5,000        22
           Improvement of Fission Track Analysis (FTA) of Urine Samples
           from the Nuclear Test Personnel Program at USDNA
 
BNL-94-258                           Volkow                $212,000        10
           Studies of Brain Aging
 
BNL-94-C20                           Barancik                    $0         0
           Geographic Information System for Long Island
 
BNL-94-C21                           Bender                      $0         0
           Studies of DNA Repair in Twins
 
BNL-94-C25                           Dilmanian               $8,000        10
           Studies of Human Anatomical  Specimens with the Multiple
           Energy Computed Tomography (MECT) System at the NSLS
 
BNL-95-243B                          Fowler                $170,000         6
           Dopamine D2 Receptor Availability Measured with Carbon-11
           Labeled Raclopride (Methylphenidate Administration)
 
BNL-95-249B                          Fowler                 $85,000         6
           Imaging the Dopamine Presynaptic Neuron with 11-C
           Methylphenidate (4 injections)
 
BNL-95-255B                          Fowler                 $95,000         9
           11-C-L-Deprenyl-D2 and 18-FDG for Study of Neurodegenerative
           Diseases
 
BNL-95-255C                          Fowler                      $0         0
           [11C]Clorgyline for MAO A Mapping and [11C]L-Deprenyl-D2 for
           MAO B Mapping
 
BNL-95-260                           Chanana             $1,000,000        10
           Boron Neutron Capture Therapy of Glioblastoma Multiforme at
           the Brookhaven Medical Research Reactor (BMRR)
 
BNL-95-260A                          Chanana               $200,000         2
           Boron Neutron Capture Therapy (BNCT) of Glioblastoma
           Multiforme at the BMRR (Prior Radiation)
 
BNL-95-261                           Wang                   $10,000         0
           Effects of Boron Neutron Capture Therapy on Glucose
           Metabolism of Glioblastoma Multiforme and Normal Brain
 
BNL-95-263                           Thomlinson             $12,000         2
           Medical Imaging with Xenon K-Edge Dichromography
 
BNL-95-C22                           Bender                      $0         0
           DNA Repair Capacity and Familial Breast Cancer
 
BNL-96-203B                          Fowler                 $70,000         4
           The Use of Parnate to Assess if 11C-Clorgyline Binds to MAO
           A in Human Brain and Liver
 
BNL-96-216B                          Fowler                $424,000        15
           Occupation of Dopamine Transporters by Pharmacological Doses
           of Cocaine
 
BNL-96-216C                          Fowler                $198,000         7
           Dopamine Transporter Occupancy by Oral Methlyphenidate
 
BNL-96-243A                          Fowler                $159,000         9
           Dopamine D2 Receptor Availability Measured with Carbon-11
           Labeled Raclopride (Naloxone Administration)
 
BNL-96-243C                          Dewey                       $0         0
           PET Scanning Study of Nefazadone and Paroxetine in Normal
           Human Volunteers
 
BNL-96-249C                          Fowler                      $0         0
           Dopamine Transporter Occupancy by Oral Methylphenidate
 
BNL-96-257B                          Kaplan                  $5,000         2
           Blood and Urine Analysis for Pu-239
 
BNL-96-258B                          Fowler                      $0         0
           Studies of Alcohol Withdrawal
 
BNL-96-265                           Springer              $409,000        11
           General Magnetic Resonance Imaging (MRI) and Spectroscopic
           (MRS) Studies of Human Subjects
 
BNL-96-266                           Chanana               $700,000         7
           BNCT of GBM at the BMRR: A Phase I/II Dose Escalation Study
 
BNL-96-267                           Thomlinson             $20,000         2
           Medical Imaging with Xenon K-Edge Dichromography
 
BNL-96-270                           Ma                          $0         0
           Weight Loss: Bone and Skeletal Muscle Homeostasis
 
BNL-96-C26                           O'Hara                $150,000         6
           The Effects Of Alarm Processing and Display on Operator and
           Plant Performance
 
Totals: 59 Project(s)                                    $5,459,000     3,965
 
Idaho National Engineering Laboratory
 
INEL-90-95-001                       Larson                $500,000         0
            Federal Aviation Administration (FAA) Explosive Detection
           System  and Independent Validation and Verification Project
 
INEL-94-95-002                       Marts                  $10,000         0
           Retractable Spiked Barrier Strip
 
INEL-94-95-003                       Marts                  $15,000         0
           Air Bag Restraint System
 
INEL-95-004                          Rice                  $235,000         4
           Concealed Weapons Detection System
 
INEL-95-005                          Makey                       $0         0
           Population Stereotypes for Crane Controls
 
Totals:  5 Project(s)                                      $760,000         4
 
Lawrence Berkeley National Laboratory
 
LBNL-75-001-H02                      Budinger              $148,000       131
           Experimental Medicine Clinical
 
LBNL-75-102-H01                      Castro                $138,000       670
           Treatment of Cancer with Heavy Charged Particles
 
LBNL-77-057-H02                      Forte                       $0         0
           Cell and Molecular Biology of Lipoprotein Metabolism
 
LBNL-79-106-H02                      Krauss                 $32,534       909
           Lipoprotein and Atherogenesis in Transgenic Animals
           (Formerly:  Metabolic & Genetic Origins of Lipoprotein
           Subclasses)
 
LBNL-79-108-H01                      Stampfer              $516,253         1
           Characterization of Human Mammary Cells
 
LBNL-80-001-H01                      Budinger                    $0         0
           Myocardial Flow, Function, and Metabolism by PET & MRI
           (Cardiovascular Flow and Metabolism)
 
LBNL-82-001-H04                      Budinger                    $0         0
           Quantitative Cardiovascular Research
 
LBNL-84-001-H03                      Budinger               $50,000         0
           Cerebral Chemical Patterns in Alzheimer's Disease
 
LBNL-84-115-H01                      Rubinstein            $195,000        65
           Lighting Technology
 
LBNL-88-073-H02                      Jagust                $120,000        42
           Longitudinal SPECT & PET Studies of Dementia
 
LBNL-88-107-H07                      Williams                    $0       400
           Lipoprotein Subfractions and Coronary Heart Disease During
           25-Year Follow-Up
 
LBNL-89-113-H01                      Levy                        $0        25
           Heavy Ion Radiosurgery
 
LBNL-90-007-H01                      Melhorn               $107,500        50
           Hemoglobin Conversion to Pro-Oxidants by Cigarette Smoke
 
LBNL-90-025-H01                      Nichols                $60,000         0
           Apolipoprotein-Specific HDL and Cholesterol Transport
 
LBNL-90-068-H01                      Narla                 $247,420        10
           Red Cell Deformability In Vitro and Survival In Vivo
 
LBNL-90-107-H02                      Williams              $212,000       185
           Weight Set Point and HDL Levels in Long-Distance Runners
 
LBNL-90-110-H01                      Nordahl                $60,000         0
           Hippocampal Metabolism in Schizophrenia
 
LBNL-91-068-H03                      Narla               $1,383,279        20
           Red Cell Membrane
 
LBNL-91-073-H01                      Jagust                $100,000        10
           Alcohol and Memory: A PET Study
 
LBNL-91-091-H01                      Chatterjee             $80,704       347
           Training and Basic Research Related to Health Effects of
           Exposure to HZE Particles
 
LBNL-91-107-H01                      Williams                    $0     1,000
           National Runner's Health Study
 
LBNL-92-065-H01                      Maguire                $12,000        20
           The Oxidant and Antioxidant Balance in Wounds (Leukocyte
           Function in Periodontal Disease)
 
LBNL-92-068-H02                      Narla                 $272,313        10
           Rheological and Adherence Properties of Sickle Cells
 
LBNL-92-106-H03                      Krauss                $234,017     1,802
           Metabolic Atherosclerosis Management Clinic and Research
           Unit
 
LBNL-92-106-H04                      Krauss                $205,724        41
           Genetic Influences on Dietary Fat Response
 
LBNL-92-107-H05                      Williams                    $0        42
           Effects of Running on HDL and LDL Subclasses of MZ Twins
 
LBNL-93-097-H01                      Bielicki                $2,000         1
           Extracellular HDL-Assembly with Apolipoprotein-AI Variants
 
LBNL-93-101-H01                      Acharya                     $0        29
           APOE4 in Alzheimer's Disease
 
LBNL-93-106-H05                      Krauss                  $8,300       108
           Genetic Determinants of Lipoprotein Changes Induced by Post
           Menopausal Hormone Replacement
 
LBNL-93-107-H04                      Williams               $27,000       105
           Effects of Diet on HDL Subclasses
 
LBNL-94-103-H01                      Jensen                 $96,000       490
           Biodosimetry for Long-Term Exposures to Low Levels of
           Ionizing Radiation
 
LBNL-94-114-H02                      Lockett                $60,000         1
           3-D Analysis of Genetic Instability in Breast Cancer
 
LBNL-95-109-H01                      Fisk                  $225,700       392
           Healthy Buildings Intervention Research
 
LBNL-95-112-H01                      Lack                        $0         0
           Pilot Study for In Vivo Sodium Content by MRI
 
LBNL-96-109-H02                      Gadgil                      $0         0
            Demonstration and Field Test of Air Jacket Technology
 
Totals: 35 Project(s)                                    $4,593,744     6,906
 
Lawrence Livermore National Laboratory
 
LLNL-84-P-101-03                     Gordon                 $70,000         5
           Human Sperm Chromatin and Chromosomes
 
LLNL-88-105                          Jones               $1,171,158       150
           Radiation Genotoxicity from Chernobyl Accident
 
LLNL-88-111                          Tucker                  $5,000        15
           Cytogenetic Studies
 
LLNL-89-104                          Kinney                 $85,000        62
           Characterization of Dentin
 
LLNL-89-106                          Biermann               $50,000        20
           Protective Breathing Equipment (Respirators) Testing
 
LLNL-89-112                          Langlois               $70,000         0
           Glycophorin A-based Somatic Mutation Analysis of Blood
           Samples from Grain Agricultural Workers that Apply
           Pesticides or Herbicides
 
LLNL-90-103                          Langlois              $120,000         0
           Somatic Cell Mutations Detected in Human Reticulocytes
 
LLNL-90-105                          Carrano                $20,000         4
           Center for Genome Research
 
LLNL-90-108                          Wyrobek                $70,000        10
           Detection of Aneuploid Human Sperm by In Situ Hybridization
           and Image Analysis
 
LLNL-91-102                          Langlois               $60,000        35
           Glycophorin A-based Somatic Cell Mutation Measurements in
           Blood Samples from Normal Individuals
 
LLNL-91-109                          Andresen              $100,000        15
           Ultratrace Hair Analysis
 
LLNL-91-114                          Felton                 $60,000         0
           Food Mutagen Metabolism
 
LLNL-92-105                          Burastero             $254,000        80
           The Effects of Ergonomically Designed Computer Keyboards on
           the Incidence of Cumulative Trauma Disorders Among VDT
           Workers
 
LLNL-94-101                          Biggs                  $21,600         6
           Immunological Treatment of Metastatic Melanoma
 
LLNL-94-103                          Vogel                   $1,000        10
           Percutaneous Absorption of Radiolabeled Chemicals in Humans
 
LLNL-94-105                          Wyrobek               $115,000        40
           Investigation of the Relationship between Numerical
           Chromosomal Aneuploidy in Sperm and Offspring:  A
           Feasibility Study
 
LLNL-94-111                          Turteltaub             $25,000         3
           Do Food Mutagens Cause Damage in Human Colon?
 
LLNL-94-112                          McEwan                $250,000         4
           Micropower Impulse Radar Human Organ Motion Studies
 
LLNL-94-113                          Tucker                $100,000        28
           Molecular Cytogenetic Studies of Human Lymphocytes
 
LLNL-94-94-116                       Azevedo                $40,000         1
           Personnel Detection and Imaging with Micropower Impulse
           Radar
 
LLNL-94-94-117                       Bogen                       $0         0
           Direct Measurement of Uptake of Toxic Chemicals from Water,
           Soil & Dust into Human Skin In Vivo, Phase I:  Aqueous Expos
 
LLNL-95-101                          Wyrobek                $70,000         0
           Sperm Aneuploidy in Men Carrying Mutations in the Cystic
           Fibrosis Gene and Who Have Congenital Absence of Vas
           Deferens
 
LLNL-95-102                          Tucker                 $96,000        40
           Cytogenetic Analyses of X-Ray Technologists
 
LLNL-95-109                          Freeman                     $0         0
           An Investigation of Human Calcium Kinetics Using 41Ca and
           Stable Isotope Labeled Calcium
 
LLNL-95-110                          Weber                  $30,000         8
           Molecular Genetics of DNA Repair
 
LLNL-95-111                          Wyrobek                $70,000         1
           Detection of Chromosomal Abnormalities in Sperm from Men
           Carrying Specific Constitutive Chromosomal Genetic Factors
 
LLNL-95-115                          Felton                $200,000         0
           Determining Metabolism Differences by Urine Analysis
 
LLNL-95-116                          Tucker                 $60,000        86
           Cytogenetic Analyses of EBDC Applicators
 
LLNL-95-117                          Pereira                 $5,800        50
           Biomechanical Differences in Playing Styles Among Pianists
           at the Dorothy Taubman Institute of Piano
 
LLNL-95-118                          Burastero               $5,000        10
           Human Factors Evaluation of the Light Exposure Calculator
 
LLNL-95-119                          Lucas                 $100,000        15
           Chromosome Painting
 
LLNL-95-121                          Lucas                 $120,000         0
           Chromosome Painting:  Chemical Clastogens
 
LLNL-95-125                          Freeman                     $0         0
           Evaluation of a 41Ca Continuous Feeding Protocol in Tandem
           with an Existing Study
 
LLNL-95-95-126                       Turteltaub            $170,000        10
           Influence of Heterocyclic Amine Metabolic Polymorphisms on
           Bioactivation of PhIP in the Human Colon
 
LLNL-95-95-127                       Sweeney                 $1,500         3
           Micro-Thin Lens for Human Vision Correction
 
LLNL-96-96-102                       Tucker                 $96,000       300
           Cytogenetic Blood Analyses of NCI-sponsored Studies
 
LLNL-96-96-103                       Turteltaub            $250,000        30
           Does Tamoxifen Cause DNA Damage in Human Tissues
 
LLNL-96-96-104                       Turteltaub             $20,000        30
           Do Trace Levels of Aflatoxin B1 Cause DNA Damage in Human
           Tissures
 
LLNL-96-96-106                       Anspaugh              $160,000        50
           Chernobyl Dosimetry
 
LLNL-96-96-107                       Sesko                  $28,000        40
           A Synergy of Science and Art
 
LLNL-96-96-108                           Pluth             $120,000       225
           Cenetic and Molecular Analysis of a Normal Human Population
 
LLNL-96-96-109                       Wyrobek               $144,000        85
           Age Effects on the Incidence of Genetic and Physiological
           Defects in Human Sperm
 
LLNL-96-96-110                       Kinney                 $82,000       100
           Characterization of Dentin
 
Totals: 43 Project(s)                                    $4,516,058     1,571
 
Los Alamos National Laboratory
 
LANL-76-90LANL07                     Reinert               $125,000         7
           Respirator Studies, Acceptance Testing Procedures for
           Air-Line Supplied Air-Suits
 
LANL-91-90 LANL 04                   Aine                  $247,000         6
           Neuromagnetic Mapping of Multiple Visual Areas in Humans
 
LANL-91-91 LANL 03                   Sklar                  $10,000         0
           Ligand-Receptor G Protein Dynamics and Neutrophil Response
 
LANL-92-92LANL03                     Reinert               $125,000         2
           Acceptance Testing of Hazardous Material Level "A"  and
           Level "B" Suits
 
LANL-93-90 LANL 05                   Johnston                    $0         0
           Personnel Verification/Identification Based on Iris
           Patterns-Bartas Iris Verification
 
LANL-94-94 LANL 02                   Reinert               $125,000         5
           Testing of Hazmat Level "A" Suits with the NASA Liquid-Air
           Breathing System
 
LANL-96-96-LANL-02                   Inkret                 $57,000        40
           Applications of Mass Spectrometry to the Detection of
           Plutonium Intakes
 
LANL-96-96 LANL 01                   Reinert                $26,000         6
           Air Line Abrasive Blast Respirators
 
LANL-96-96 LANL 03                    Reinert               $48,000         2
           Heat Stess and Durability Testing, Frahm-Tex Cool Suit
 
LANL-96-96 LANL 04                   Reinert               $125,000         5
            Evaluation of Sensors and Methods for Auditory Canal
           Temperature Measurements
 
LANL-96-96 LANL 05                   Marrone               $100,000         0
           Improved Methods for Detection of Beryllium Sensitivity
 
Totals: 11 Project(s)                                      $988,000        73
 
Oak Ridge Institute for Science and Education
 
ORAU-78-96                           Goans                  $50,000         3
           Use of Ca-DTPA and Zn-DTPA for Chelation Therapy of Heavy
           Metals
 
ORAU-80-58                           Littlefield               $500         5
           Whole Blood Procurement, Consent for Research Waiver Form
           and Payment Authorization
 
ORAU-80-60                           Cragle                $149,000     3,350
           Comprehensive Epidemiology Study of Department of Energy
           Atomic Workers
 
ORAU-80-61                           Goans                  $25,000         3
           The DTPA Registry Follow-Up Program
 
ORAU-80-62                            Goans                      $0         0
           The Department of Energy  Equal to or Greater Than 5 Rem
           Study Follow-up Program
 
ORAU-80-63                           Goans                  $25,000       150
           The U.S. Radiation Accident Registry Follow-Up Program
 
ORAU-89-60a                          Cragle                  $4,000     1,879
           Amendment - Comprehensive Epidemiology Study of Department
           of Energy Atomic Workers
 
ORAU-91-80                           Dupree Ellis                $0         0
           Study of Morbidity and Mortality From Selected Causes Among
           Oak Ridge Y-12 Sheet Metal Workers
 
ORAU-91-81                           Goans                       $0         0
           Use of Prussian Blue for Internal Decontamination of
           Radiocesium
 
ORAU-91-82a                          Littlefield             $2,000        40
           Studies to Establish and Define ORAU Laboratory Standards
           for Lymphocyte Proliferation Tests (LPT) [Prev
           Title:"Studies to Establish and Define ORAU Laboratory
           Standards for Lymphocyte Transformation Tests"  ]
 
ORAU-92-87                           Cragle              $1,000,000       217
           Oak Ridge Y-12 Beryllium Workers Follow-Up Study, Phase II:
           Screening for Beryllium Sensitivity and Definitive Diagnosis
           of Chronic Beryllium Disease
 
ORAU-93-88                           Cragle                 $98,000         0
           Follow-up Study of Morbidity Among Mercury Exposed Y-12
           Workers  (Old Title: A Study of the Health Effects of
           Exposure to Elemental Mercury: A Follow-up of Mercury
           Exposed Workers at the Y-12 Plant  )
 
ORAU-94-89                           Cragle                 $40,000         0
           Childhood Cancer and Parental Exposure to Ionizing Radiation
 
ORAU-94-91                           McFee                  $20,000         6
           Establishing Background Level of Chromosomal Translocations
           (OLD TITLE: Biodosimetry of Exposed Populations )
 
ORAU-95-83                           Dupree Ellis           $22,300       472
           Identification and Abstraction of Death Certificates for the
           Agency for Toxic Substances and Disease Registry.  (Previous
           Title: Identification and Abstraction of Death Certificates
           for National Registry of Persons Exposed to Hazardous Sub
 
ORAU-95-95                           Toohey    (chan        $55,320         0
            Treatment of Metastases Refactory to Conventional Treatment
           (OLD TITLE:Prospective Treatment Planning for Palliative
           Therapy of Bone Metastasis with Sn-117m )
 
ORAU-96-98                           Tankersley             $78,000       234
           Improved Systems for Worker Exposure Surveillance
 
Totals: 17 Project(s)                                    $1,569,120     6,359
 
Oak Ridge National Laboratory
 
ORNL-93-17                           Jenkins               $270,000     1,686
            Measurement of Environmental Tobacco Smoke Constituents in
           Occupied Spaces
 
ORNL-93-28                           Wolfe                       $0         5
           Relating Ecological Indicators to Societal Values
 
ORNL-94-33                           Buchanan               $25,000         3
           Development of Methods to Obtain Fingerprints from Children
           for Forensic Applications
 
ORNL-94-38                           Draper                $500,000        10
           Advanced Robotics for Remanufacturing and Aircraft Support
           Functions
 
ORNL-95-45                           Gailey                $480,000        50
           Physiological Responses to Electric and Magnetic Fields
           (EMF) in Humans
 
ORNL-95-47                           Gailey                 $40,000       192
           Melatonin Levels of Electric Utility Workers
 
ORNL-95-50                           Gailey                 $50,000        20
           Development of Recommendations for Personal Exposure
           Measurement of Electric and Magnetic Fields
 
ORNL-96-53                           Gailey                      $0         0
            Survey of Personal Magnetic Field Exposure
 
ORNL-96-54                           Gailey                      $0         0
            Development of Field Exposure Predictions Models
 
ORNL-96-55                           Jenkins                $30,000         0
           Environmental Tobacco Smoke: Composition, Exposure, and
           Measurement
 
Totals: 10 Project(s)                                    $1,395,000     1,966
 
Pacific Northwest National Laboratory
 
PNNL-95-5                            Thrall                 $40,000         4
           Field Applicability of an Exposure-To-Risk Monitoring System
 
PNNL-96-94-4                         Thrall                      $0         0
            PBPK Breath Analysis Instrumentation Demonstration
 
PNNL-96-1                            Collins                $30,000         3
             Imaging Neurological Processes of the Human Brain
 
PNNL-96-20                           Cameron                     $0         0
           Study of Heat Stress and Performance in Carpenters at DOE
           Sites   (Courtesy Review)
 
PNNL-96-95-3                             Toth                    $0         0
           Noninvasive Approach to Testing for H. Pylori Infections
           Using Breath Analysis
 
Totals:  5 Project(s)                                       $70,000         7
 
Rocky Flats Environmental Technology Site
 
RFET-68-RF-94-02                     Gottschall                  $0         0
           United States Transuranium Registry
 
RFET-80-RF-94-01                     Gottschall            $745,000       200
           Former Radiation Worker Recall Program
 
RFET-80-RF-94-03                     Gottschall                  $0        25
           1965 Fire Group
 
RFET-87-RF-94-05                     Stange                $200,000       400
           Rocky Flats Antibody Assay
 
RFET-91-RF-94-86                     Stange              $1,646,000     1,000
           Rocky Flats Beryllium Health Surveillance Program
 
RFET-93-RF-94-04                     Falk                        $0         0
           Short Study to Evaluate New Ultra-Sensitive Analysis Method
           for Measuring Occupational Exposure to Plutonium-239
 
Totals:  6 Project(s)                                    $2,591,000     1,625
 
Sandia National Laboratories
 
SNL-92-02                            Morimoto                    $0         0
           3D Ultrasound Imaging for Diagnostic Imaging (formerly
           Non-Invasive Scanning Techniques for Prosthetic
           Applications)
 
SNL-93-06                            Hooper                      $0         0
           Mathematical Modeling Approach to Quantitative Retrospective
           Exposure Assessment of Potential Occupational Exposures to
           Mixed Organic Solvents at Sandia National Laboratories, NM.
 
SNL-94-01                            Love                   $15,000        50
           Personal Status Monitor
 
SNL-94-12                            Osbourn                $10,000         7
           Calibration and Benchmarking Data for Machine Vision and
           Image Classification
 
SNL-95-12                            Ladd                        $0         0
            Human Presence Detection Utilizing a Chemical Agent Monitor
 
SNL-95-02                            Bouchier                $4,000        90
           Evaluation of the Performance of the IriScan Biometric
           Identity Device
 
SNL-95-05                            Bouchier                    $0         0
           Evaluation of the Performance of the Facial Image Biometric
           Identifiers
 
SNL-95-06                            Bouchard               $50,000         4
           Acoustic Data Acquisition From Human Subjects
 
SNL-95-09                            Rodriguez              $10,000         0
           Performance Evaluations of Biometric Identification Devices
           II
 
SNL-95-10                            Bouchard               $40,000       100
           Video and Acoustic Data Acquisition From Human Subjects for
           Personnel Identity Verification
 
SNL-95-11                            Aurand                      $0         0
           Radar Detection of Concealed Weapons
 
SNL-95-13                            Buckle                 $50,000       208
           Evaluation of the performance of Voice Verification Devices
 
SNL-96-04                            Spencer                $85,000        11
           Commuter Aircraft Visual Inspection Reliability
 
SNL-96-05                            Tucker                  $3,500         9
           Visual Observer Tests
 
Totals: 14 Project(s)                                      $267,500       479
 
 
DOE Facility Totals:  210 Projects               $22,289,422    22,960
 

Non-DOE Facilities:

 
                                     Principal                        # Human
Project Identifier                   Investigator           Funding   Subjects
 
Sloan-Kettering Institute for Cancer Research
 
SKI-86-ER60407                       Larson                 $20,000         2
           Improving Cancer Treatment with Cyclotron Produced
           Radionuclides
 
SKI-95-ER62039                       Larson                      $0         0
           Pharmacokinetics of Genetically Engineered Antibody Forms
           Using Positron Emission Tomography
 
Totals:  2 Project(s)                                       $20,000         2
 
University of Vermont
 
UVT-83-DE-FG02-87ER60502             Albertini             $356,000        15
           The Development of In Vitro Mutagenicity Testing Systems
           Using T-Lymphocytes
 
Totals:  1 Project(s)                                      $356,000        15
 
Azienda Ospedaliera Policlinico di Modena
 
MDNA-93-DEFG0293ER61714              Saltini                $61,228       160
           Structural and Functional Basis of Genetic Susceptibility to
           Chronic Beryllium Disease
 
Totals:  1 Project(s)                                       $61,228       160
 
Beckman Laser Institute/UC Irvine
 
UCI-91-ER61227                       Berns                     $500        27
           A center of excellence for the medical application of lasers
 
Totals:  1 Project(s)                                          $500        27
 
Beth Israel-Deaconess Medical Center
 
BIDMC-94-1                           Zamenhof              $550,000         2
           Phase-I BNCT Trial of Peripheral Melanoma (in FY95 database
           see project NEMC-87-DEFG0287ER6060, New England Medical
           Center)
 
BIDMC-94-2                           Zamenhof              $550,000         2
            Phase-I BNCT Trial of Glioblastoma Multiforme and
           Metastatic Melanoma to the Brain (in FY95 database, see
           project NEMC-87-DEFG0287ER6060, New England Medical Center)
 
Totals:  2 Project(s)                                    $1,100,000         4
 
Columbia University
 
CU-91-2923R                          Soares                $350,000        16
           Chromosome-specific cDNAs/STSs
 
Totals:  1 Project(s)                                      $350,000        16
 
Columbia University - Eye Research
 
CU-95-95EH89658                      Worgul                $199,451         0
           Ocular Radiation Effects in Chernobyl  Liquidators
 
Totals:  1 Project(s)                                      $199,451         0
 
Department of Molecular Biology, Princeton University
 
PU-96-DE-FG02-96ER62202              Fresco                      $0         2
            Development of Affinity Technology for Isolating Individual
           Human Chromosomes by Third Strand Binding
 
Totals:  1 Project(s)                                            $0         2
 
Inhalation Toxicology Research Institute
 
ITRI-94-IRB#94-004                   Cheng                       $0         0
           In Vivo Measurements of Aerosol Deposition in the Nasal and
           Oral Airways of Human Subjects
 
ITRI-95-IRB#94-034                   Lewis                  $30,000         0
           Deposition of  Inhaled Toxicants in the Olfactory System
 
ITRI-95-IRB#95-030                   Guilmette             $255,000        10
           Pilot Study Measurement of Lead (210Pb) in Former Uranium
           Miners
 
ITRI-96-IRB # 96-019                 Guilmette             $240,000        20
           In Vivo Measurement of 210Pb in Former Uranium Miners
 
Totals:  4 Project(s)                                      $525,000        30
 
Johns Hopkins University
 
JHU-87-DEFG0288ER60655               Swift                 $100,000        10
           Regional Aerosol Deposition in Human Upper Airways
 
Totals:  1 Project(s)                                      $100,000        10
 
Massachusetts Institute of Technology
 
MIT-86-ER60448                       Thilly                $250,000         4
           Comparative Mutagenesis of Human Cells In Vivo and In Vitro
 
Totals:  1 Project(s)                                      $250,000         4
 
Michigan State University
 
MSU-93-FG02-87ER60524                McCormick                   $0         2
           Malignant Transformation of Human Fibroblasts by Neutrons
           and Gamma Radiation:  Relationship to Mutations Induced
 
Totals:  1 Project(s)                                            $0         2
 
National Academy of Sciences
 
NAS-90-DEFG0590ER60960               Gilman             $19,600,000     3,658
           Activities of National Academy of Sciences in Relation to
           the Radiation Effects Research Foundation (RERF)
 
Totals:  1 Project(s)                                   $19,600,000     3,658
 
St. Mary's Hospital Cancer Research Institute
 
SMHCRI-94-DE-FG03-94ER61842          Anderson              $166,077       111
           Examination of Genetic Alterations in Preneoplastic Lesions
           of the Lung from Uramium Miners
 
SMHCRI-95-DE-FG03-95ER62060/A0       Anderson              $114,488        59
           Identification of Human Lung Cancer Susceptibility Genes
 
SMHCRI-97-DE-FG02-90E60939           Saccomanno             $66,924       270
           Eary Lung Cancer Detection in Uranium Miners with Abnormal
           Sputum Cyology
 
Totals:  3 Project(s)                                      $347,489       440
 
Stanford University
 
SU-86-M-1272-01                      Giacomini             $173,117         7
           K-Edge Subtraction Angiography with Synchrotron X-rays
 
Totals:  1 Project(s)                                      $173,117         7
 
University of California, Berkeley
 
UCB-92-ER61393                       Duster                $200,508         5
           Pathways to Genetic Screening
 
Totals:  1 Project(s)                                      $200,508         5
 
University of California, Los Angeles
 
UCLA-47-87ER60615                    Eisenberg               $8,000         2
           Structural Biology and Molecular Medicine Research
           Program/Nuclear Medicine Applications
 
UCLA-92-639                          Small                       $0         0
           Mapping Dopamine Receptors with F-188 fluoroethylspiperone
           (see project UCLA1-47-87ER60615, subproject 92-11-639-3 in
           1995 and 1996 database)
 
UCLA-92-640                          Small                       $0         0
           Dopamine Transport and Storage Measured with DOPA
 
UCLA-95-036                          Small                       $0         0
           Dopamine Transport and Storage Measured with [18F]
           Fluoro-L-m-Tyrosine (see project UCLA1-47-87ER60615,
           sub-project 95-01-036 in 1995 and 1996 database)
 
UCLA-95-117                          Schelbert              $46,000        13
           Measurement of Myocardial Blood Flow with N-13 Ammonia (see
           project numbered UCLA1-47-87ER60615, sub-project  92-12-683
           for previous year information)
 
UCLA-96-082                          Gambhir                     $0         0
            Sparing/Recovery of Function after Hemispherectomy:
           Analysis with Functional Imaging
 
UCLA-96-426                          Czernin                     $0         0
           Response of Coronary Vasomotion to Intravenous L-Arginine
 
UCLA-96-450                          Czernin                     $0         0
           Significance of Cardiac Allograft Vasculopathy
 
Totals:  8 Project(s)                                       $54,000        15
 
University of California, Los Angeles - School of Medicine
 
UCLA-87-ER60548                      Gatti                 $310,000        40
           Human Gene for Radiation Hypersensitivity
 
Totals:  1 Project(s)                                      $310,000        40
 
University of Chicago
 
UCHI-86-DEFG0286ER60408              Rowley              $1,237,741       150
           Correlation of Chromosome Patterns in Leukemic Cells of
           Patients with Exposure to Chemicals and/or Radiation
 
Totals:  1 Project(s)                                    $1,237,741       150
 
University of Michigan Hospitals
 
UMH-79-NS15655                       Kuhl                   $67,500         8
           Positron Emission Tomography (PET) Study of the Biochemistry
           and Metabolism of the Central Nervous System (CNS)
 
UMH-86-NS24896                       Kuhl                  $198,000        90
           Emission Computed Tomography of Local Cerebral Function
 
UMH-87-DE-FG02-87ER60561             Kuhl                   $30,750        15
           Advancing PET Science for New Measures of Brain Function
 
UMH-93-N149310462                    Jonides               $112,220        62
           Working Memory as Revealed by Positron Emission Tomography
           (PET)
 
Totals:  4 Project(s)                                      $408,470       175
 
University of Tennessee Medical Center-Knoxville
 
UTMC-92-IRB-0104                     Smith                       $0         0
           A Consortium to Develop the Medical Uses of NMR Imaging, NMR
           Spectroscopy, and Positron Emission Tomography
 
UTMC-93-IRB-0555                     Kabalka                $90,000         2
           An Evaluation of Fluorine-18 Labeled BPA-F in Patients with
           Glioblastoma Multiforme Using Positron Emission Tomography
           (PET)
 
Totals:  2 Project(s)                                       $90,000         2
 
University of Washington
 
UWA-92-26-009-E                      Trask                 $332,000         5
           Analytical Cytogenetics and Gene Mapping
 
Totals:  1 Project(s)                                      $332,000         5
 
Washington State University
 
WASU-68-50181                        Kathren             $1,550,000       886
           United States Transuranium and Uranium Registries
 
Totals:  1 Project(s)                                    $1,550,000       886
 
Washington University
 
WUSM-93-61659                        Bergmann              $324,000         1
           Detection and Assessment Using Position Emission Tomography
           of Genetically Determined Defects in Myocardial Fatty Acid
           Utilization
 
Totals:  1 Project(s)                                      $324,000         1
 
 
Non-DOE Facility Totals:   42 Projects           $27,589,504     5,656
 
Grand Totals:  252 Projects                      $49,878,926    28,616