USDOE Human Subjects Research Database Summary, Fiscal Year 2000

Listing of project identifier, principal investigator, funding, number of human subjects, and project title.



DOE Facilities:
Project IdentifierPrincipal Investigator Funding# Human
Subjects
Ames Laboratory
AMES-98-248103 Yeung $170,000.00 9
Single Molecule DNA Assay and Immunoassay
AMES-99-176404 Yeung $275,000.00 9
High-Speed High-Throughput Mutation Detection
Site Totals: 2 Projects $445,000.00 18
Argonne National Laboratory
ANL-95-93003 Huberman $0.00 0
Analysis of Differentiation Markers in Normal and Leukemic Blood Cells
ANL-00-00001 Brown-VanHoozer $65,000.00 33
Speaker Recognition Through NLP and CWT Modeling
Site Totals: 2 Projects $65,000.00 33
Brookhaven National Laboratory
BNL-77-146 Sutherland $0.00 0
DNA Repair - Human and E. Coli Photoreactivating Enzymes
BNL-89-222 Wielopolski $223,285.00 12
New and Old Models in Body Composition: Ethnic Specificity
BNL-89-225 Wielopolski $223,285.00 1
Nutritional and Intestinal Consequences of Immunodeficiency States
BNL-91-C15 Breitenstein $175,000.00 3,200
Health Surveillance System
BNL-91-C24 Sutherland $95,000.00 0
Photoreactivation in Human Skin
BNL-94-144C Fowler $9,000.00 3
Evaluation of 18-FDG in the Diagnosis of Glucose Metabolism in the Human Body (Tumors)
BNL-94-144E Fowler $9,000.00 3
Evaluation of 18-FDG in the Diagnosis of Glucose Metabolism in the Human Body (Alzheimer's)
BNL-94-258 Fowler $0.00 0
Studies of Brain Aging
BNL-94-C33 Dunn $0.00 0
Vaccine Intervention for Lyme Borreliosis
BNL-95-260A Coderre $50,000.00 0
Boron Neutron Capture Therapy (BNCT) of Glioblastoma Multiforme at the BMRR (Prior Radiation)
BNL-96-265 Springer $499,000.00 31
General Magnetic Resonance Imaging (MRI) and Spectroscopic (MRS) Studies of Human Subjects
BNL-96-266 Coderre $500,000.00 0
BNCT of GBM at the BMRR: A Phase I/II Dose Escalation Study
BNL-96-268 Fowler $0.00 0
Brain Imaging Studies in Obesity
BNL-96-270 Wielopolski $223,285.00 15
Weight Loss: Bone and Muscle Skeletal Homeostasis
BNL-97-264 Susskind $5,000.00 1
99m Tc DTPA Lung Clearance in Radiation Injury
BNL-97-271 Morrison $0.00 0
Quantitative Studies on the Oncogenic and Cytogenetic Effects of Energetic Iron Particles in Mammalian Cells
BNL-98-266A Coderre $750,000.00 0
Boron Neutron Capture Therapy of Glioblastoma Multiforme at the Brookhaven Medical Research Reactor: A Phase I/II Dose Escalation Study (FDA IND 43,317, Protocol #5)
BNL-98-277 Fowler $49,000.00 3
Brain Imaging Studies in Methamphetamine Abusers
BNL-98-278 Hetherington $120,000.00 5
Spectroscopic Evaluation of Human Epilepsy
BNL-98-279 Fowler $90,000.00 9
PET Studies of the Effects of Tobacco Smoke on the Human Brain
BNL-98-280 Volkow $75,000.00 11
Spectroscopic Studies in Drug Abusers
BNL-98-281 Pan $30,000.00 0
Cerebral Metabolism in Ketosis and Epilepsy: A Spectroscopic Study at 4T
BNL-98-282 Pan $150,000.00 30
Evaluation of Multiple Sclerosis by 1H MR Spectroscopy
BNL-98-283 Lee $30,000.00 5
Cerebral Metabolism in Functional Stimulation: A Combined 1H-13C Magnetic Resonance and PET Study
BNL-98-284 Fowler $0.00 0
PET Evaluation of the Effect of Ginko Biloba on Brain Monoamine Oxidase (MAO)
BNL-98-285 Pan $60,000.00 1
Regional Ethanol Uptake Kinetics and MRI Visibility of Human Brain by 1H MRI Imaging
BNL-98-286 Coderre $100,000.00 0
Two Fraction Boron Neutron Capture Therapy of Debulked Glioblastoma Multiforme at the Brookhaven Medical Research Reactor: A Phase I/II Dose Escalation Study (FDA IND 43,317, Protocol #6)
BNL-98-287 Coderre $100,000.00 0
Two Fraction Boron Neutron Capture Therapy of Non-Debulked Glioblastoma Multiforme at the Brookhaven Medical Research Reactor: A Phase I/II Dose Escalation Study (FDA IND 43,317, Protocol #7)
BNL-98-288 Coderre $100,000.00 0
Boron Neutron Capture Therapy of Recurrent Glioblastoma Multiforme at the Brookhaven Medical Research Reactor: A Phase I/II Dose Escalation Study (FDA IND 43,317, Protocol #8)
BNL-98-289 Fowler $20,000.00 1
PET Studies of L-Deprenyl (Selegiline)
BNL-98-291 Fowler $0.00 0
Determination of DAT Occupancy by Oral Doses of Methylphenidate
BNL-98-292 Fowler $0.00 0
Determination of DAT Occupancy by Intravenous Methlyphenidate
BNL-98-293 Fowler $0.00 0
Determination of DAT Occupancy by Cocaine as a Function of Different Routes of Administration (Intravenous, Snorted and Smoked)
BNL-98-294 Fowler $200,000.00 10
Determination of DAT Occupancy by Cocaine after an Oral Dose of Methylphenidate
BNL-98-295 Fowler $0.00 0
PET Studies of Cocaine Abuse: Response to Methylphenidate
BNL-98-296 Rooney $75,000.00 4
Brain Water Content and Blood-Brain Barrier Permeability in Multiple Sclerosis
BNL-99-297 Fowler $90,000.00 6
PET Studies of Dopamine Receptor Availability: Effects of Exercise
BNL-99-298 Fowler $105,000.00 7
PET Studies of Radiotracers and Labeled Drugs in the Human Body: [11C]Clorgyline
BNL-99-300 Fowler $0.00 0
PET Studies of Dopamine Receptor Availability: Dose Response of Methylphenidate
BNL-99-301 Fowler $26,000.00 2
PET Studies of Alcoholism: Measurement of Brain Glucose Metabolism and Dopamine Activity in Alcoholics During Early and Late Detoxification
BNL-99-302 Fowler $0.00 0
PET Studies of Alcoholism: Measurement of Brain Metabolism and Brain Dopamine Concentration with 18FDG and 11C-Raclopride
BNL-99-303 Ding $0.00 0
PET Studies in Humans with C-11 Labeled Methadone
BNL-99-304 Fowler $96,000.00 8
PET Studies of Cocaine Abuse: Evaluation of Brain GABA Activity
BNL-99-305 Fowler $0.00 0
PET Studies of Phentermine
BNL-99-306 Fowler $40,000.00 2
PET Studies of the Relationship Between Dopamine Transporter Occupancy by Methylphenidate and Changes in Brain Dopamine
BNL-99-307 Lee $150,000.00 37
Evaluation of Cerebral Blood Vessel Function in Drug Abusers
BNL-99-308 Wang $21,000.00 1
Effect of Boron Neutron Capture Therapy on Glucose Metabolism of Glioblastoma Multiforme and Normal Brain
BNL-99-310 Fowler $0.00 0
Comparison of Brain Function as Measured in the MRI Environment to that Measured in the PET Environment
BNL-99-312 Rooney $0.00 0
Magnetic Field Dependence of Water Proton Relaxation in Human Brain
BNL-99-313 Pan $0.00 0
MR Spectroscopic Imaging of Glutamate in Malignant Gliomas of Brain Tumor Patients with Epilepsy
BNL-99-314 Lee $150,000.00 1
Mechanisms of Fat Induced Insulin Resistance
BNL-99-317 Fowler $75,000.00 5
PET Studies of Alcoholism: Measurement of the Effect of Alcohol Intoxication on Brain Glucose Metabolism
BNL-99-318 Pan $30,000.00 2
MR Measurements of Cerebral Metabolism in Fasting and Visual Stimulation
BNL-99-319 Sammi $0.00 0
MR Investigation of Brain Metabolism in Fasting and Ketosis Using Beta-Hydroxybutyrate Infusions
BNL-99-320 Fowler $0.00 0
PET Studies of the Brain Serotonin Systems with [11C]N-Methylspiroperidol
BNL-99-C31 Breitenstein $0.00 0
Brookhaven National Laboratory Employee Cancer Incidence Evaluation
BNL-99-C32 Hsiao $0.00 0
Hair Test for Breast Cancer
BNL-00-321 Jacobsen $0.00 0
Brain Response to Intravenous Methylphenidate with and without Pretreatment of Oral Methylphenidate
BNL-00-322 Breitenstein $0.00 0
Calcium and Zinc DTPA for use in Treating Radionuclide Internal Depositions
BNL-00-323 Lee $0.00 0
Simultaneous Functional Magnetic Resonance Imaging and Event-Related Potential Recording
BNL-00-324 Ding $90,000.00 0
PET Studies of Catechol-O-Methyltransferase (COMT) with [18F]Ro-41-0960
BNL-00-325 Fowler $0.00 0
PET Studies of Monoamine Oxidse (MAO)
BNL-00-326 Fowler $0.00 0
Brain Dopamine and Reward and Motivation in Controls and Substance Abusers
BNL-00-327 Coderre $500,000.00 4
Follow-Up Protocol for the Boron Neutron Capture Therapy Clinical Trial at Brookhaven National Laboratory
BNL-00-328 Goldstein $0.00 0
Perception of Pleasure and Control of Behavior in Drug Addiction: An fMRI Study
BNL-00-329 Sammi $15,000.00 8
MR Spectroscopic Imaging of Multiple Sclerosis: Effects of Donzepil Therapy in a Double Blinded Trial
BNL-00-330 Sammi $10,000.00 2
Measurements of GABA in Human Brain by 1H Spectroscopy
BNL-00-331 Wielopolski $260,000.00 16
Weight Loss: Bone and Skeletal Muscle Homeostasis
BNL-00-337 Dunn $0.00 0
Platelet mRNA Profiles as Indicators of Early Thrombosis
BNL-00-339 Breitenstein $0.00 0
Medical Surveillance of Current BNL Employees Identified as Beryllium Exposed
BNL-00-340 Maynard $6,000.00 0
Follow-Up Study of Alcohol and Cocaine Abusers, Comparing Addiction History and Dopamine Receptor Density
BNL-00-341 Fowler $0.00 0
PET Studies in Cocaine Abusers: Effects of Deprenyl
BNL-00-344 Rooney $10,000.00 0
Blood Brain Barrier Permeability and the Menstrual Cycle
Site Totals: 73 Projects $5,634,855.00 3,446
Idaho National Engineering and Environmental Laboratory
INEEL-90-95-001 Miller $100,000.00 20
Federal Aviation Administration (FAA) Explosive Detection System and Independent Validation and Verification Project
INEEL-95-004 Polk $49,000.00 3
Concealed Weapons Detection System
INEEL-97-INEEL-97-001 Thompson $20,000.00 15
Development of Immunological Sensor Test Kits for Forensic Samples
INEEL-98-4 Nigg $10,000.00 10
Tissue-Boron Analysis
INEEL-00-INEEL-00-02 Hill $2,000.00 20
Human System Simulation Enterprise - Multimedia in Procedures Part 2
INEEL-00-INEEL-2000-003 Blackman $4,500.00 45
INEEL Human-System Simulation Enterprise: Multimedia in Composition
Site Totals: 6 Projects $185,500.00 113
Lawrence Berkeley National Laboratory
LBNL-75-001-H02 Budinger $3,000.00 3
Experimental Medicine Clinical
LBNL-77-057-H02 Rubin $0.00 0
Studies of Lipoproteins and Lipid Protein Interactions
LBNL-79-106-H02 Krauss $50,000.00 534
Lipoproteins and Atherogenesis in Transgenic Animals
LBNL-79-108-H01 Stampfer $598,000.00 1
Characterization of Human Mammary Cells
LBNL-80-001-H01 Budinger $0.00 0
Myocardial Flow, Function, and Metabolism by PET & MRI
LBNL-84-001-H03 Budinger $15,000.00 2
Alzheimer's Disease as a Systemic Disorder
LBNL-88-107-H07 Williams $0.00 0
Lipoprotein Subfractions and Coronary Heart Disease During 25-Year Follow-Up
LBNL-90-007-H01 Melhorn $0.00 0
Hemoglobin Conversion to Pro-Oxidants by Cigarette Smoke
LBNL-90-068-H01 Narla $38,480.00 2
Red Cell Deformability In Vitro and Survival In Vivo
LBNL-90-107-H02 Williams $0.00 0
Weight Set Point and HDL Levels in Long-Distance Runners
LBNL-91-068-H03 Narla $140,000.00 12
Red Cell Membrane
LBNL-91-107-H01 Williams $550,000.00 70,000
National Runner's Health Study
LBNL-92-065-H01 Maguire $0.00 0
The Oxidant and Antioxidant Balance in Wounds (Leukocyte Function in Periodontal Disease)
LBNL-92-068-H02 Narla $28,900.00 2
Rheological and Adherence Properties of Sickle Cells
LBNL-92-106-H04 Krauss $300,000.00 267
Genetic and Metabolic Factors Affecting Response of Lp(a) to Dietary Fat
LBNL-92-107-H05 Williams $0.00 70
Effects of Running on HDL and LDL Subclasses of MZ Twins
LBNL-94-093-H01 Tribble $10,000.00 1
Modulation of Oxidant Stress-Mediated Atherosclerosis (Formerly: Oxidative Implications of Lipoprotein Heterogeneity)
LBNL-94-114-H02 Lockett $40,000.00 6
3-D Analysis of Genetic Instability in Breast Cancer
LBNL-95-109-H01 Fisk $0.00 0
Healthy Buildings Intervention Research
LBNL-96-068-H04 Narla $0.00 0
Cellular Consequences of Hemoglobin Membrane Structure
LBNL-97-001-H05 Budinger $0.00 0
122-I Generator and Radiotracers for Perfusion Studies
LBNL-97-057-H03 Forte $0.00 0
Plasma Antioxidative Enzymes as Indicators of Smoke Injury
LBNL-98-106-H06 Krauss $25,000.00 192
Genetic Testing for Evaluation of Heart Disease Risk
LBNL-98-107-H06 Williams $345,000.00 2,000
National Health Survey on the Internet
LBNL-98-110-H03 Nordahl $0.00 0
Sex Differences of Dopamine Metabolism
LBNL-98-139-H01 Moses $0.00 0
Breast Cancer Specific PET Instrumentation
LBNL-99-106-H07 Krauss $2,000.00 4
Evaluation of the Safety and Efficacy of Nicostatin (A combination tablet of Niacin extended-release/Lovastatin immediate-release): A Dose-Response Study
LBNL-99-107-H07 Williams $0.00 0
Effects of Genes on the Relationship of Lifestyle to Disease
LBNL-99-109-H02 Fisk $0.00 0
Health and Productivity Intervention Study
LBNL-99-133-H02 Snow $0.00 16
Development of Improved Methods for the Detection of Sensitivity to Beryllium in Human Beings and the Identification of Immunologic and Genetic Factors Which Determine this Sensitivity
LBNL-99-146-H01 Hazen $0.00 0
Bioremediation Education, Science and Technology Program
LBNL-99-99-H01 Goth-Goldstein $0.00 0
Gene-Environment Interactions Related to Breast Cancer
LBNL-00-001-H07 Budinger $0.00 0
Brain Tumor Hypoxia Detection
LBNL-00-106-H08 Krauss $3,000.00 3
Evaluation of the Safety and Efficacy of Nicostatin (A combination tablet of Niacin Extended Release/Lovastatin Immediate Release): An Open Label Extension Study
LBNL-00-106-H09 Krauss $46,000.00 0
Arterial Endothelial Function: An Epidemiological Study
LBNL-00-111-H02 Sextro $40,000.00 3
Indoor Measurements of Environmental Tobacco Smoke
LBNL-00-164-H01 Thiel $0.00 30
An Evaluation of Controlled Negative Pressure and Ambient Aerosol Based Instruments in Quantitation Respirator Fit Testing
LBNL-00-165-H01 Conrad $0.00 0
The Detection of Bone Metastases Through Variations in Isotopic Calcium and Phosphate Signatures with Bodily Fluids and Soft Tissue
LBNL-00-166-H01 Floyd $0.00 1
Control Study for Iodine-125 Thyroid In Vivo Analysis
Site Totals: 39 Projects $2,234,380.00 73,149
Lawrence Livermore National Laboratory
LLNL-88-105 Jones $1,400,000.00 10
Radiation Genotoxicity from Chernobyl Accident
LLNL-88-111 Tucker $100.00 3
Cytogenetic Studies
LLNL-89-106 Biermann $0.00 0
Protective Breathing Equipment (Respirators) Testing
LLNL-90-105 Carrano $0.00 0
LLNL Human Genome Center
LLNL-91-102 Langlois $170,000.00 7
Glycophorin A-based Somatic Cell Mutation Measurements in Blood Samples from Normal Individuals
LLNL-92-105 Tittiranonda $1,000.00 0
The Effects of Ergonomically Designed Computer Keyboards on the Incidence of Cumulative Trauma Disorders among VDT Workers
LLNL-94-105 Wyrobek $180,000.00 0
Investigation of the Relationship between Numerical Chromosomal Aneuploidy in Sperm and Offspring
LLNL-95-126 Turteltaub $10,000.00 2
Influence of Heterocyclic Amine Metabolic Polymorphisms on Bioactivation of PhIP in the Human Colon
LLNL-96-103 Turteltaub $10,000.00 4
Does Tamoxifen cause DNA Damage in Human Tissues
LLNL-96-106 Lucas $66,000.00 0
Chernobyl Dosimetry
LLNL-96-109 Wyrobek $180,000.00 0
Age Effects on the Incidence of Genetic and Physiological Defects in Human Sperm
LLNL-96-113 Vogel $32,800.00 3
The Dynamics of Folate Metabloism in Adults
LLNL-96-114 Colston $150,000.00 2
Optical Diagnosis of Periodontal Tissues
LLNL-97-110 Stubbs $127,000.00 0
Generation of Contiguous Sequence-Ready DNA Clones in Human and Mouse
LLNL-98-102 Lucas $70,000.00 0
Evaluation of Chromosome Damage to Uranium Workers in Namibia for Assessment of Health Risk.
LLNL-98-104 Vogel $0.00 0
Elucidating Dynamics of Beta-Carotene Metabolism in Adults
LLNL-98-106 Mendelsohn $100,000.00 0
Melanoma and other Mortality Rates in LLNL Employees
LLNL-98-111 Tucker $600,000.00 2
Chromosome Aberration Persistence Study
LLNL-98-97-116 Layton $241,000.00 0
LLNL/AHS Study of Home-Cooked Foods
LLNL-99-104 Wyrobek $88,000.00 0
Molecular Genetic Analysis of Infertility in Men
LLNL-99-106 Lucas $0.00 0
Long-term Bioindicator for Radiation Exposure
LLNL-99-109 Vogel $15,400.00 2
Absorbed Beta-Carotene: A Retinoid Source in Humans
LLNL-99-115 Kinney $90,000.00 67
Characterization of Dentin
LLNL-99-117 Jones $170,000.00 64
Methods Development for Studies of Genetic Damage and DNA Repair Function
LLNL-99-118 Johnson $500.00 0
Naturally Occuring Uranium in Urine
LLNL-99-119 Demos $310,000.00 10
Endoscopic Sub-Surface Optical Imaging for Cancer Detection
LLNL-99-121 Keating $26,000.00 0
Improved Measurement of Cholinesterase Inhibition
LLNL-99-130 Burastero $1,000.00 0
Botulinum Toxiod Vaccine
LLNL-99-131 Hartmann Sianta $140,000.00 11
PEREGRINE 3-D Monte Carlo Dose Calculations
LLNL-00-101 Wyrobek $150,000.00 9
Analyses of Spermatozoa from Testicular Cancer Patients Exposed to Radiotherapy
LLNL-00-102 Mohrenweiser $20,000.00 50
A Model for Genetic Susceptibility: Melanoma
LLNL-00-103 Felton $96,000.00 6
Quantifying the Effects of Preventive Foods on the Metabolism of a Prostate Carcinogen in Humans and in Prostate Cells Grown in Culture
LLNL-00-106 Bogen $0.00 0
Prostate Cancer Screening and Dietary HA Exposure in African Americans
LLNL-00-107 Chang $50,000.00 6
Intracranial Hematoma Detection Using Impulse Radar
LLNL-00-108 Turteltaub $1,000.00 1
Study to Assess the Safety of Teremifene in the Uterus of Women: Comparison with Tamoxifen
LLNL-00-109 Turteltaub $0.00 0
Study to Assess the Safety of Tereminfene in the Liver of Women: Comparison with Tamoxifen
LLNL-00-111 Darrow $1,000.00 51
A Prospective Evaluation of a New Device to Detect Biliary Microlithiasis
LLNL-00-113 Burastero $1,000.00 0
Use of Chelating Agents in Radiation Accidents
LLNL-00-114 Tucker $260,000.00 224
Smoking During Pregnancy: Chromosome Damage in Mothers and Newborns
LLNL-00-116 Knize $10,000.00 66
PhIP Metabolites in Human Urine After Consumption of Cooked Meats
Site Totals: 40 Projects $4,767,800.00 600
Los Alamos National Laboratory
LANL-52-91 LANL 06 Voelz $0.00 16
Manhattan Project Plutonium Workers Health Study
LANL-76-90 LANL 07 Reinert $215,000.00 8
Acceptance Testing for Air-Line Supplied Air-Suits
LANL-91-03 Sklar $0.00 0
Ligand-Receptor G Protein Dynamics and Neutrophil Response
LANL-96-05 Marrone $200,000.00 180
The Development of Improved Methods for the Detection of Individual Sensitivity to Beryllium
LANL-98-01 Wray $100,000.00 10
Development and Testing of A Fieldable Prototype Noninvasive Intracranial Pressure Measurement System
LANL-98-02 Kraus, Jr. $550,000.00 4
Neuromagnetic Mapping of Functional Centers in the Human Brain
LANL-98-04 Lehnert $130,000.00 0
Use of Human Peripheral Blood Samples in Structural Biology of Bacterial Toxins
LANL-99-04 Hollander $20,000.00 110
Anthropometric Profile of Glovebox Operators
LANL-00-00-03 Mallett $20,000.00 8
Neutron Extremity Dosimetry Based on Monte Carlo Computations of Magnetic Resonance Images
LANL-00-01 Kraus, Jr. $440,000.00 0
Electromagnetic Mapping of Cardiac Function in the Human Heart
LANL-00-02 Seymour $40,000.00 110
Research Study: LANL Intern Program Evaluation
LANL-00-03 Reinert $70,000.00 9
Aircrew Process/MOPP Exchange Testing
Site Totals: 12 Projects $1,785,000.00 455
Oak Ridge Institute for Science and Education
ORAU-78-96 Goans $55,000.00 6
Use of Ca-DTPA and Zn-DTPA for Chelation Therapy of Heavy Metals
ORAU-79-63 Goans $26,000.00 70
The U.S. Radiation Accident Registry Follow-Up Program
ORAU-80-58 Cragle $285.80 20
Whole Blood Procurement, Consent for Research Waiver Form and Payment Authorization
ORAU-80-60 Cragle $112,148.00 13,719
Comprehensive Epidemiology Study of Department of Energy Atomic Workers
ORAU-80-61 Goans $26,000.00 6
The DTPA Registry Follow-Up Program
ORAU-89-60a Cragle $0.00 0
Amendment - Comprehensive Epidemiology Study of Department of Energy Atomic Workers: National Death Index
ORAU-91-81 Goans $0.00 0
Use of Prussian Blue for Internal Decontamination of Radiocesium
ORAU-91-83 Ellis $16,615.95 0
Identification and Abstraction of Death Certificates for National Registry of Persons Exposed to Hazardous Substances
ORAU-92-102 Aldrich $860,000.00 133
Former Radiation Worker Medical Surveillance Program at Rocky Flats (Formerly, Medical Monitoring Program for Former Radiation Workers at Rocky Flats"
ORAU-92-87 Cragle $0.00 0
Y-12 Beryllium Workers Follow-up Study, Phase II: Screening for Beryllium Sensitivity and Definitive Diagnosis of Chronic Beryllium Disease
ORAU-94-106 Ellis $771,419.36 61,538
Department of Energy Epidemiologic Surveillance Data Center
ORAU-99-87a Cragle $4,025,067.00 2,747
Beryllium Workers Follow-up Study, Phase II: Screening for Beryllium Sensitivity and Definitive Diagnosis of Chronic Beryllium Disease. Amendment - to add Former Beryllium Workers at all DOE sites where Beryllium was used.
ORAU-00-104 Eisele $33,400.00 0
Updated Study of the Accelerated Access Authorization Process
ORAU-00-105 Eisele $229,300.00 39
Infrared Thermography to Detect Intentional Deception
ORAU-00-107 Tardif $150,000.00 124
Vaccine Safety Focus Groups
ORAU-00-ORAU-00-108 Elllis $25,635.80 3,838
Update of a Mortality Study of Titanium Dioxide Workers
Site Totals: 16 Projects $6,330,871.91 82,240
Oak Ridge National Laboratory
ORNL-93-17 Jenkins $50,000.00 2,007
Measurement of Environmental Tobacco Smoke Constituents in Occupied Spaces
ORNL-94-33 Buchanan $200,000.00 34
Characterization of Components of Fingerprints
ORNL-94-38 Draper $0.00 0
Advanced Robotics for Remanufacturing and Aircraft Support Functions
ORNL-98-17a Jenkins $30,000.00 24
Measurement of Environmental Tobacco Smoke Constituents in Occupied Spaces. Phase III
ORNL-98-56 Sega $0.00 20
Study of Neurotransmitters in Children with ADD or ADHD
ORNL-99-57 Tufano $0.00 0
Driver Research by the Human Systems Research Group
ORNL-99-58 Spelt $0.00 0
In-Vehicle Information Integration Study
ORNL-00-60 Tufano $0.00 0
LDRD Driver Research: Phase II
Site Totals: 8 Projects $280,000.00 2,085
Pacific Northwest National Laboratory
PNNL-91-2000-13 McMakin $25,000.00 30
Holographic Milllimeter Wave Real-Time Surveillance Imaging System
PNNL-93-3-1 Fix $185,000.00 44,500
Comprehensive Epidemiologic Data Resource (CEDR) Related Tasks
PNNL-96-4 Richman $2,000.00 18
Field Evaluation of Polarized and Full Spectrum Polarized Lighting
PNNL-97-14 Hanlen $300,000.00 3,500
Handwriting Science, Moving From Art to Science
PNNL-97-8 Thrall $10,000.00 5
Fundamental Research on Solvent-laden Soils
PNNL-99-5 Stapp $10,000.00 2
Hanford Cultural Resources Project
PNNL-99-6 Bilyard $5,000.00 0
Communicating Effectively with NABIR stakeholders
PNNL-00-1 Richman $20,000.00 30
Energy Efficient Lighting Applications and Productivity at the Internal Revenue Service Andover Data Center Facility
PNNL-00-24 Bunn $12,000.00 0
Groundwater/Vadose Zone Integration - System Assessment Capability
Site Totals: 9 Projects $569,000.00 48,085
Rocky Flats Environmental Technology Site
RFET-91-RF-94-06 Newman $716,894.00 762
Rocky Flats Beryllium Health Surveillance Program: Current Workers
Site Totals: 1 Project $716,894.00 762
Sandia National Laboratories
SNL-98-01 Sandoval $0.00 0
Border Warning/Intrusion Detection System
SNL-98-02 Swahlan $5,000.00 4
Power and Thermal Tool Testing
SNL-98-03 Zelicoff $0.00 0
Hepatitis C Research Study
SNL-99-06 Wenner $200,000.00 42
Visual Inspection Reliability Program
SNL-99-08 Buckle $0.00 0
Facial Verification System Evaluation
SNL-00-05 Wu $5,000.00 2
Measurement of Air Exchange Rates Inside a Moving Vehicle
SNL-00-10 Griffith $0.00 40
Genetic Markers for Early Onset Familial Breast Cancer
SNL-00-11 Griffith $0.00 40
Genetic Susceptibility to Asthma
SNL-00-12 Wessendorf $50,000.00 5
Pedomass Personnel Tracker
SNL-00-17 Wright $61,000.00 50
Facial Verification System Evaluation
SNL-00-20 Craft $2,000.00 0
Computer Architecture for Telemedicine Health Care Delivery Systems
Site Totals: 11 Projects $323,000.00 183
Sub-Totals: 219 Projects $23,337,300.91 211,169


Non-DOE Facilities:
Project IdentifierPrincipal Investigator Funding# Human
Subjects
Agency for Toxic Substances and Disease Registry
ATSDR-96-1624 Gist $0.00 7,000
National Exposure Registry: Iodine-131 Subregistry Site Specific Protocol, Hanford Nuclear Reservation, State of Washington
Site Totals: 1 Project $0.00 7,000
Beckman Laser Institute/UC Irvine
BLI-91-ER61227 Berns $1,600.00 53
A Center of Excellence for Laser Applications in Medicine
Site Totals: 1 Project $1,600.00 53
Beth Israel Deaconess Medical Center
BIDMC-94-1 Busse $100,000.00 0
Phase-I BNCT Trial of Peripheral Melanoma
BIDMC-96-2 Busse $1,540,000.00 0
Phase-I BNCT Trial of Glioblastoma Multiforme and Metastatic Melanoma to the Brain
Site Totals: 2 Projects $1,640,000.00 0
City University of New York
CUNY-98-H-0002 Spielman $5,000.00 3
Near Infrared Spectroscopy (NIRS) in Patients with Obstructive Sleep Apnea Syndromes
CUNY-98-H-0009 Spielman $3,000.00 5
Imaging the Brain with Near Infrared Light During Sleep
CUNY-98-H9938-C Alfano $0.00 0
Breast Cancer Program: Optical Mammography
CUNY-99-H9939-C Alfano $0.00 0
Skin Subsurface Imaging Using Spectral and Polarization Imaging
CUNY-99-MTC/YALE Alfano $3,000.00 3
Hormone Levels Probed by Fluorescence Spectroscopy of the Female Genitalia
Site Totals: 5 Projects $11,000.00 11
Columbia University
CU-93-62433 Bergmann $216,613.00 3
Detection and Assessment Using Position Emission Tomography of Defects in Myocardial Fatty Acid Utilization Leading to Cardiomyopathy
Site Totals: 1 Project $216,613.00 3
Columbia University - Eye Research
CU-95-95EH89658 Worgul $433,357.00 11,710
Ocular Radiation Effects in Chernobyl Liquidators
Site Totals: 1 Project $433,357.00 11,710
Consortium for Risk Evaluation w/ Stakeholder Participation
CRESP-95-X-0887 Wartenberg $70,000.00 16,489
An Update of The Worker Cohort Mortality Study at Nuclear Fuels Production Facility on the Savannah River site
CRESP-96-27-0009-E Takaro $0.00 0
Laboratory Evaluation of Field Collected Cells
CRESP-97-27-0228-C Takaro $12,624.00 8
Screening for Chronic Beryllium Disease at Hanford
Site Totals: 3 Projects $82,624.00 16,497
Lovelace Respiratory Research Institute
LRRI-95-IRB#96027 Guilmette $300,000.00 34
In Vivo Measurements of Lead-210 in Former Uranium Miners
Site Totals: 1 Project $300,000.00 34
Medical University of South Carolina, Environmental Biosciences Program
MUSCBP-95-6241 Pandey $4,000.00 378
Trichloroethylene Exposure and Host Genetic Factors in Autoimmune Diseases
Site Totals: 1 Project $4,000.00 378
National Academy of Sciences (NAS)
NAS-96-DEFC03-97SF21318 Douple $11,300,000.00 2,656
Activities of National Academy of Sciences in Relation to the Radiation Effects Research Foundation (RERF)
Site Totals: 1 Project $11,300,000.00 2,656
National Institute for Occupational Safety and Health
NIOSH-92-002 Schubauer-Berig $178,900.00 105,000
Cohort Mortality Study of Idaho National Engineering and Environmental Laboratory (INEEL)
NIOSH-93-003 Taulbee $368,900.00 38,000
Cohort Mortality Study of Portsmouth Naval Shipyard (PNS)
NIOSH-93-013 Morin $49,200.00 23,000
Epidemiologic Evaluation of Cancer and Occupational Exposure at Rocky Flats
NIOSH-94-018 Wilkinson $0.00 68,338
Mortality Among Female Nuclear Weapons Workers
NIOSH-94-019 Bigbee $0.00 12
Glycophorin A Biodosimetry in I-131 Treated Patients
NIOSH-95-004 Wenzl $224,700.00 95,000
Leukemia Case-Control Study
NIOSH-95-005 Robinson $194,924.00 47,941
Study of Multiple Myeloma among Workers at the Oak Ridge Gaseous Diffusion Plant (K-25)
NIOSH-95-014 Cardis $3,936.00 600,000
International Collaborative Study of Nuclear Industry Workers
NIOSH-95-015 Pepper $0.00 5,894
Prevention of Stress and Health Consequences of Downsizing and Reorganization
NIOSH-95-016 Rosenman $0.00 5,111
Chronic Beryllium Disease Among Beryllium-Exposed Workers
NIOSH-95-017 Newman $0.00 109
Beryllium Disease Natural History and Exposure Response
NIOSH-95-021 Newman $0.00 170
Lung Fibrosis in Plutonium Workers
NIOSH-95-022 Rosenman $0.00 100
Study of Heat Stress and Performance in Carpenters at DOE Sites
NIOSH-95-033 Barnhart $0.00 47,601
Comprehensive Occupational Health Surveillance
NIOSH-95-034 Bingham $0.00 450
Work Histories - Evaluating New Participatory Methods
NIOSH-95-035 Ruttenber $0.00 867
Sentinel Exposure Event Surveillance/Evaluation at DOE Sites
NIOSH-95-036 Froines $0.00 0
Hazard Surveillance in the Defense Nuclear Industry
NIOSH-96-008 Grajewski $0.00 4,668
Cohort Mortality Study of Pantex Plant, Amarillo, Texas
NIOSH-96-010 Wald $0.00 59
Acute Radiation Syndrome in Russian Nuclear Workers
NIOSH-96-023 Wing $94,546.00 33,472
Ionizing Radiation and Mortality Among Hanford Workers
NIOSH-97-001 Elliott $0.00 9,000
Case-Control Study of the Portsmouth Gaseous Diffusion Plant
NIOSH-97-007 Robinson $155,300.00 5,000
Cohort Mortality Study of DOE Chemical Laboratory Workers
NIOSH-97-009 Silver $189,150.00 28,000
Multi-State Case-Control Study of Lung Cancer and External Ionizing Radiation
NIOSH-97-026 Lambert $0.00 500
Epidemiologic Studies to Evaluate Health Effects of Uranium Milling
NIOSH-98-032 Brodkin $0.00 200
Surveillance Methods for Solvent-Related Hepatotoxicity
NIOSH-99-006 Xue $88,080.00 8,318
Correcting for Measurement Errors in Radiation Exposure
NIOSH-99-011 Newman $217,779.00 235
Dose of Beryllium Causing Sensitization and Disease
NIOSH-99-012 Pinney $185,714.00 7,248
Radon and Cigarette Smoking Exposure Assessment in Fernald Workers
NIOSH-99-020 Stram $217,169.00 6,806
Measurement Error Methods for Underground Miner Studies
NIOSH-99-024 Cardis $110,747.00 140
Reconstruction of Doses for Chernobyl Liquidators
NIOSH-99-025 Ruttenber $189,963.00 867
Uncertainty Analysis for Characterizing Plutonium Exposure/Lung Cancer Estimates
Site Totals: 31 Projects $2,469,008.00 1,142,106
Sloan-Kettering Institute for Cancer Research
SKI-86-ER60407 Larson $12,000.00 11
Improving Cancer Treatment with Cyclotron Produced Radionuclides
SKI-95-ER62039 Larson $0.00 0
Pharmacokinetics of Genetically Engineered Antibody Forms Using Positron Emission Tomography
Site Totals: 2 Projects $12,000.00 11
St. Mary's Hospital Saccomanno Research Institute
SMHSRI-95-DE-FG03-95ER62060/A0 Carstea $0.00 0
Identification of Human Lung Cancer Susceptibility Genes
SMHSRI-97-DE-FG02-90E60939 Saccomanno $0.00 0
Early Lung Cancer Detection in Uranium Miners with Abnormal Sputum Cytology
Site Totals: 2 Projects $0.00 0
The Ohio State University
OSU-95-95H0240 Goodman $58,400.00 0
Pharmacokinetics and Biodistribution of Sodium Borocaptate in Patients with Anaplastic Astrocytomas / Glioblastoma Multiforme
Site Totals: 1 Project $58,400.00 0
University of California, Los Angeles
UCLA-92-640 Small $0.00 0
Dopamine Transport and Storage Measured with DOPA
UCLA-93-654 Schelbert $0.00 0
Assessment of Myocardial Viability by N-13 Ammonia, F-18 Deoxyglucose and Positron Emission Tomography
UCLA-95-117 Schelbert $14,000.00 53
Measurement of Myocardial Blood Flow with N-13 Ammonia
UCLA-95-450 Czernin $0.00 0
Significance of Cardiac Allograft Vasculopathy
UCLA-96-082 Gambhir $0.00 0
Sparing/Recovery of Function after Hemispherectomy: Analysis with Functional Imaging
UCLA-96-426 Schelbert $0.00 0
Response of Coronary Vasomotion to Intravenous L-Arginine
UCLA-98-021 Eisenberg $0.00 0
Human Subject Research Under Structural Biology & Molecular Medicine Research Program
UCLA-98-039 Small $7,000.00 17
Beta-Amyloid Probes of Alzheimer's Disease
UCLA-98-062 Czernin $0.00 0
FDG PET for Evaluating Patients with a Pelvic Mass
UCLA-99-061 Schelbert $0.00 0
Repeat Measurements of Myocardial Blood Flow with N-13 Ammonia and PET During Cold Pressor Testing
Site Totals: 10 Projects $21,000.00 70
University of Michigan Hospitals
UMH-87-DE-FG02-87ER60561 Kuhl $40,000.00 20
Advancing PET Science for New Measures of Brain Function
Site Totals: 1 Project $40,000.00 20
University of Nevada Las Vegas
UNLV-00-DE-FG03-00ER63059 Rice $1,405,000.00 0
Medical Records Knowledge Discovery and Information Management for Radiation Workers
Site Totals: 1 Project $1,405,000.00 0
University of Tennessee Medical Center-Knoxville
UTMC-93-IRB-0555 Kabalka $35,000.00 0
An Evaluation of Fluorine-18 Labeled BPA-F in Patients with Glioblastoma Multiforme Using Positron Emission Tomography (PET)
Site Totals: 1 Project $35,000.00 0
University of Vermont
UVT-97-DE-FG07-96ER62331 Albertini $0.00 2
A Novel Biomarker for Beryllium Sensitization in Humans
Site Totals: 1 Project $0.00 2
University of Washington
UWA-92-UWA-95-1085-E08 Trask $595,650.00 9
Analytical Cytogenetics and Gene Mapping
Site Totals: 1 Project $595,650.00 9
Washington State University
WASU-68-50181 Filipy $1,096,001.00 900
United States Transuranium and Uranium Registries
Site Totals: 1 Project $1,096,001.00 900
Sub-Totals: 69 Projects $19,721,253.00 1,181,460


Former Workers Project projects:
Project IdentifierPrincipal Investigator Funding# Human
Subjects
Alaska Department of Environmental Conservation
ADEC-00-DE-FG08-99NV13726 Ringen $327,922.00 61
Amchitka Island Workers Medical Surveillance Program
Site Totals: 1 Project $327,922.00 61
Boston University School of Public Health
BUSPH-96-DE-FC03-96SF21261 Pepper $790,000.00 744
Medical Surveillance for Former Department of Energy Workers at the Nevada Test Site
Site Totals: 1 Project $790,000.00 744
Colorado University Health Sciences Center
CUHSC-96-DE-FC03-96SF21259 Ruttenber $500,000.00 522
Medical Monitoring Program for Former Rocky Flats Workers
Site Totals: 1 Project $500,000.00 522
Johns Hopkins University School of Hygiene and Public Health
JHUSHP-97-DE-FC03-98SF21541 Schwartz $600,000.00 770
Medical Surveillance for Former Department of Energy Workers
Site Totals: 1 Project $600,000.00 770
Medical University of South Carolina
MUSC-97-DE-FC03-97SF21513 Hoel $799,639.00 343
Savannah River Site Former Production Workers Health Surveillance Program
Site Totals: 1 Project $799,639.00 343
Paper, Allied-Industrial, Chemical and Energy Workers International Union
PACE-96-DE-FC03-96SF21260 Wages $1,000,000.00 1,419
DOE Gaseous Diffusion Plants K-25, Portsmouth, and Paducah Current and Former Workers Medical Surveillance Program
PACE-97-DE-FC03-97SF21512 Wages $790,000.00 274
Medical Surveillance For Former INEEL Workers
Site Totals: 2 Projects $1,790,000.00 1,693
The Center to Protect Workers' Rights
CPWR-96-DE-FC03-96SF21262 Ringen $790,000.00 900
Hanford Building Trades Medical Screening Project
CPWR-97-DE-FC03-97SF21514 Ringen $790,000.00 1,000
The Augusta Building Trades Medical Screening Program for the Savannah River Site
Site Totals: 2 Projects $1,580,000.00 1,900
University of Cincinnati
UOC-96-DE-FC03-96SF21263 Bingham $0.00 326
Medical Surveillance Program for Construction Workers at Oak Ridge, TN : Phase II-LPT
Site Totals: 1 Project $0.00 326
University of Iowa
UI-00-DE-FC03-00EH00025 Fuortes $515,000.00 0
Burlington Atomic Energy Commision Plant Former Worker Survey
Site Totals: 1 Project $515,000.00 0
University of Washington
UOW-96-DE-FC03-96SF21258 Brodkin $791,499.00 22,000
Medical Surveillance Program/Former DOE Hanford Production Workers
Site Totals: 1 Project $791,499.00 22,000
Sub-Totals: 12 Projects $7,694,060.00 28,359

Grand Totals: 300 Projects $50,752,613.91 1,420,988